Acetarsone

Acetarsone

SCHEMBL27363340

CC(=O)Nc1cc([As](=O)(O)O)ccc1O.[SiH4]

nearest known ligand 0.97

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.97
POLB P06746 2/20 0.97
PHPT1 Q9NRX4 2/20 0.97
SMN1; SMN2 Q16637 1/20 0.97
GAA P10253 1/20 0.61
KMT2A Q03164 3/20 0.54
KDM4E B2RXH2 2/20 0.51
HDAC1 Q13547 2/20 0.51
APOBEC3A P31941 1/20 0.51
GFER P55789 1/20 0.51
APOBEC3G Q9HC16 1/20 0.51
PKM P14618 1/20 0.49
MAPT P10636 2/20 0.46
NPC1 O15118 1/20 0.46
RAB9A P51151 1/20 0.46
MEN1 O00255 2/20 0.44
CYP2C19 P33261 3/20 0.42
USP2 O75604 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
TSHR P16473 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetarsone SCHEMBL29604580 0.98 LMNA (1.00) LMNAPOLBPHPT1SMN1; SMN2GAA
Acetarsone SCHEMBL156373 0.98 LMNA (1.00) LMNAPOLBPHPT1SMN1; SMN2GAA
Acetarsone SCHEMBL27508847 0.97 LMNA (0.97) LMNAPOLBPHPT1SMN1; SMN2GAA
Acetarsone SCHEMBL27701891 0.97 LMNA (0.97) LMNAPOLBPHPT1SMN1; SMN2GAA
Acetarsone SCHEMBL19947468 0.97 LMNA (0.97) LMNAPOLBPHPT1SMN1; SMN2GAA
Acetarsone SCHEMBL27571635 0.97 LMNA (0.97) LMNAPOLBPHPT1SMN1; SMN2GAA
Acetarsone SCHEMBL27524425 0.95 POLB (0.94) LMNAPOLBPHPT1SMN1; SMN2GAA
Acetarsone SCHEMBL27621004 0.95 POLB (0.94) LMNAPOLBPHPT1SMN1; SMN2GAA
Acetarsone SCHEMBL27831969 0.95 LMNA (0.94) LMNAPOLBPHPT1SMN1; SMN2GAA
Acetarsone SCHEMBL27431867 0.94 LMNA (0.91) LMNAPOLBPHPT1SMN1; SMN2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101189280-A Aqueous dispersions of silylated polyethers BLUESTAR SILICONES FRANCE (FR) 2008-05-28 CN claimed
CN-104471076-A Sensing device and method DNA ELECTRONICS LTD 2015-03-25 CN disclosed
CN-101600664-B Glass substrates coated or laminated with multiple layers of cured silicone resin compositions DOW CORNING 2013-02-06 CN disclosed
CN-101675096-B Nanomaterial-filled silicone composition and reinforced silicone resin film DOW CORINING CORP 2012-12-26 CN disclosed
CN-101675096-A Nanomaterial-filled silicone composition and reinforced silicone resin film DOW CORINING CORP 2010-03-17 CN disclosed
CN-101600664-A Glass substrates coated or laminated with multiple layers of cured silicone resin compositions DOW CORNING INC (US) 2009-12-09 CN disclosed
CN-101595166-A Silicone resin, silicon composition, coated substrate and enhancing silicone resin DOW CORNING (US) 2009-12-02 CN disclosed
CN-101189280-A Aqueous dispersions of silylated polyethers BLUESTAR SILICONES FRANCE (FR) 2008-05-28 CN disclosed
CN-101177486-A Preparation method of fluorine silicon rubber base rubber GUANGDONG XINLI SPECIAL RUBBER (CN) 2008-05-14 CN disclosed
CN-1302048-C Fluorine-silicon compounded rubber stock and method for making same SHANGHAI 3F NEW MATERIALS CO L (CN) 2007-02-28 CN disclosed
CN-1878884-A Method of metallizing a silicone rubber substrate DOW CORNING (US) 2006-12-13 CN disclosed
CN-1839172-A Carbazolyl-functional cyclosiloxane, silicone composition and organic light-emitting diode DOW CORNING (US) 2006-09-27 CN disclosed
CN-1249129-C Aqueous dispersion based on viscous silicone oils crosslinkable by condensation into an adhesive elastomer, which can be used in particular as a mastic or paint, and method for the production thereof RHODIA CHIME (FR) 2006-04-05 CN disclosed
CN-1702098-A Fluorine-silicon compounded rubber stock and method for making same SHANGHAI 3F NEW MATERIALS CO L (CN) 2005-11-30 CN disclosed
CN-1441822-A Aqueous dispersion based on viscous silicone oils crosslinkable by condensation into an adhering elastomer for use in particular as coatings or paints RHODIA CHIME (FR) 2003-09-10 CN disclosed
CN-1071349-C Crosslinked emulsions of pre-formed silicon modified organic polymers DOW CORNING (US) 2001-09-19 CN disclosed
CN-1151998-A Crosslinked emulsions of pre-formed silicon modified organic polymers DOW CORNING (US) 1997-06-18 CN disclosed
CN-1140186-A Crosslinked emulsions with optimum consistency and handling without thickeners DOW CORNING (US) 1997-01-15 CN disclosed