Acetarsone

Acetarsone

SCHEMBL29604580

CC(=O)Nc1cc([As](=O)(O)O)ccc1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 1.00
POLB P06746 2/20 1.00
PHPT1 Q9NRX4 2/20 1.00
SMN1; SMN2 Q16637 1/20 1.00
GAA P10253 1/20 0.63
KMT2A Q03164 3/20 0.56
KDM4E B2RXH2 2/20 0.53
HDAC1 Q13547 2/20 0.53
APOBEC3A P31941 1/20 0.53
GFER P55789 1/20 0.53
APOBEC3G Q9HC16 1/20 0.53
PKM P14618 1/20 0.50
MAPT P10636 2/20 0.47
NPC1 O15118 1/20 0.47
RAB9A P51151 1/20 0.47
MEN1 O00255 2/20 0.46
CYP2C19 P33261 3/20 0.44
USP2 O75604 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
ALDH1A1 P00352 3/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetarsone SCHEMBL156373 1.00 LMNA (1.00) LMNAPOLBPHPT1SMN1; SMN2GAA
Acetarsone SCHEMBL27701891 0.98 LMNA (0.97) LMNAPOLBPHPT1SMN1; SMN2GAA
Acetarsone SCHEMBL27508847 0.98 LMNA (0.97) LMNAPOLBPHPT1SMN1; SMN2GAA
Acetarsone SCHEMBL27571635 0.98 LMNA (0.97) LMNAPOLBPHPT1SMN1; SMN2GAA
Acetarsone SCHEMBL19947468 0.98 LMNA (0.97) LMNAPOLBPHPT1SMN1; SMN2GAA
Acetarsone SCHEMBL27363340 0.98 LMNA (0.97) LMNAPOLBPHPT1SMN1; SMN2GAA
Acetarsone SCHEMBL27621004 0.97 POLB (0.94) LMNAPOLBPHPT1SMN1; SMN2GAA
Acetarsone SCHEMBL27524425 0.97 POLB (0.94) LMNAPOLBPHPT1SMN1; SMN2GAA
Acetarsone SCHEMBL27831969 0.97 LMNA (0.94) LMNAPOLBPHPT1SMN1; SMN2GAA
Acetarsone SCHEMBL27431867 0.95 LMNA (0.91) LMNAPOLBPHPT1SMN1; SMN2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112912364-B Effect of catalyst concentration and solid activator on nickel-mediated coupling of olefins/carbon dioxide with acrylates 切弗朗菲利浦化学公司 2023-07-07 CN disclosed
CN-116239460-A Continuous process for converting olefins and carbon dioxide to acrylic acid salts by means of a solution phase reactor 切弗朗菲利浦化学公司 2023-06-09 CN disclosed
CN-116217370-A High porosity aromatic resins as promoters in the production of acrylic esters by coupling reactions of olefins and carbon dioxide 切弗朗菲利浦化学公司 2023-06-06 CN disclosed
CN-110799480-B Process and catalyst system for forming alpha, beta-unsaturated carboxylic acids or salts thereof 切弗朗菲利浦化学公司 2023-01-03 CN disclosed