SCHEMBL27363365

SCHEMBL27363365

CN(C)c1ccc(N2CCCCC2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.53
MAPT P10636 5/20 0.52
ALOX15 P16050 4/20 0.52
L3MBTL1 Q9Y468 4/20 0.52
KDM4E B2RXH2 4/20 0.52
HSD17B10 Q99714 3/20 0.52
NPC1 O15118 2/20 0.52
USP2 O75604 2/20 0.52
POLB P06746 2/20 0.52
HTT P42858 2/20 0.52
RAB9A P51151 2/20 0.52
GAA P10253 2/20 0.52
NPSR1 Q6W5P4 2/20 0.52
MEN1 O00255 1/20 0.52
TP53 P04637 1/20 0.52
THRB P10828 1/20 0.52
RECQL P46063 1/20 0.52
KMT2A Q03164 1/20 0.52
TDP1 Q9NUW8 3/20 0.50
LMNA P02545 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL27659481 0.98 ALDH1A1 (0.55) ALDH1A1MAPTALOX15L3MBTL1KDM4E
SCHEMBL2201868 0.98 ALDH1A1 (0.51) ALDH1A1MAPTALOX15L3MBTL1KDM4E
SCHEMBL30408019 0.93 ALDH1A1 (0.51) ALDH1A1MAPTALOX15L3MBTL1KDM4E
SCHEMBL9658891 0.87 SLC2A1 (0.49) ALDH1A1MAPTALOX15L3MBTL1KDM4E
SCHEMBL14982059 0.86 RAB9A (0.54) ALDH1A1MAPTALOX15L3MBTL1KDM4E
SCHEMBL10473357 0.86 MEN1 (0.54) ALDH1A1MAPTALOX15L3MBTL1KDM4E
SCHEMBL10472949 0.86 MEN1 (0.54) ALDH1A1MAPTALOX15L3MBTL1KDM4E
SCHEMBL11638317 0.85 SLC2A1 (0.46) ALDH1A1MAPTALOX15L3MBTL1KDM4E
SCHEMBL5950454 0.85 MAPT (0.53) ALDH1A1MAPTALOX15L3MBTL1KDM4E
SCHEMBL10473803 0.84 MEN1 (0.56) ALDH1A1MAPTALOX15L3MBTL1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103756257-A Thermosetting epoxy resin composition and use thereof SHENGYI TECHNOLOGY CO LTD 2014-04-30 CN claimed
CN-1566117-A Fluorine quinolone compounds and synthetic method thereof BEIJING DOUBLE CRANE PHARMACEU (CN) 2005-01-19 CN claimed
CN-109833484-A A kind of Pegylation polylysine-hydroxycamptothecin nano grain preparation method without methotrexate and containing methotrexate (MTX) 湖南师范大学 2019-06-04 CN disclosed
CN-104254521-B Trans-2-decylenic acid derivative and the medicine that contains it NIPPON ZOKI PHARMACEUTICAL CO.,LTD. (JP) 2016-05-04 CN disclosed
CN-104177313-A 2,5-DISUBSTITUTED ARYLSULFONAMIDE CCR3 ANTAGONISTS AXIKIN PHARMACEUTICALS INC 2014-12-03 CN disclosed
CN-102186856-B Pyrrolopyrimidines as CDK inhibitors NOVARTIS AG 2014-09-24 CN disclosed
CN-104059066-A Diazacarbazoles And Methods Of Use GENENTECH INC 2014-09-24 CN disclosed
CN-103788100-A Pyrrolopyrimidine compounds as CDK inhibitors NOVARTIS AG 2014-05-14 CN disclosed
CN-103756257-A Thermosetting epoxy resin composition and use thereof SHENGYI TECHNOLOGY CO LTD 2014-04-30 CN disclosed
CN-102414191-B 4 -isopropylphenyl glucitol compounds as sgltl inhibitors TAISHO PHARMACEUTICAL CO LTD 2014-04-16 CN disclosed
CN-101835779-B Purine derivatives useful as PI3 kinase inhibitors HOFFMANN LA ROCHE 2014-01-29 CN disclosed
CN-1297442-A 5-aminoindeno [1,2-c] pyrazol-4-ones as anti-cancer and anti-proliferative agents DU PONT PHARM CO (US) 2001-05-30 CN disclosed
CN-1064042-C Intermediate of benzazepine derivative YAMANOUCHI PHARMA CO LTD (JP) 2001-04-04 CN disclosed
CN-1270960-A Process for preparing growth hormone secretagogue PFIZER PROD INC (US) 2000-10-25 CN disclosed
CN-1234790-A Oligosaccharide synthesis ALCHEMIA CO LTD (AU) 1999-11-10 CN disclosed
CN-1218047-A Novel imidazolidine derivatives, their preparation, their use and pharmaceutical preparations comprising them HOECHST MARION ROUSSEL DE GMBH (DE) 1999-06-02 CN disclosed
CN-1040748-C Benzazepine derivatives, pharmaceutical compositions and intermediates thereof YAMANOUCHI PHARMA CO LTD (JP) 1998-11-18 CN disclosed
CN-1198437-A Intermediate of benzazepine derivative YAMANOUCHI PHARMA CO LTD (JP) 1998-11-11 CN disclosed
CN-1129934-A Benzazepine derivatives, pharmaceutical compositions and intermediates thereof YAMANOUCHI PHARMA CO LTD (JP) 1996-08-28 CN disclosed
CN-87105777-A Heterogeneous ring compound 1988-04-06 CN disclosed