Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.70 |
| ▸ | METAP2 | P50579 | 1/20 | 0.67 |
| ▸ | RAB9A | P51151 | 5/20 | 0.65 |
| ▸ | TSHR | P16473 | 3/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.59 |
| ▸ | PYGL | P06737 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
| ▸ | CASP3 | P42574 | 1/20 | 0.58 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.58 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.58 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28729469 | 0.90 | KMT2A (0.65) | KMT2AMETAP2RAB9ATSHRHSD17B10 | |
| SCHEMBL12368122 | 0.87 | KMT2A (0.79) | KMT2AMETAP2RAB9ATSHRHSD17B10 | |
| SCHEMBL28850318 | 0.85 | KMT2A (0.59) | KMT2AMETAP2RAB9ATSHRHSD17B10 | |
| SCHEMBL29963747 | 0.85 | ALDH1A1 (0.55) | KMT2AMETAP2RAB9ATSHRHSD17B10 | |
| SCHEMBL28475214 | 0.84 | NPC1 (0.74) | KMT2ARAB9ASMN1; SMN2MAPTMAPK1 | |
| SCHEMBL11743614 | 0.83 | NPC1 (0.72) | RAB9AHSD17B10SMN1; SMN2GAAMAPK1 | |
| SCHEMBL7721970 | 0.83 | HSD17B10 (0.69) | KMT2ARAB9ATSHRHSD17B10SMN1; SMN2 | |
| SCHEMBL6802094 | 0.83 | KMT2A (1.00) | KMT2AMETAP2RAB9ATSHRHSD17B10 | |
| SCHEMBL11784909 | 0.83 | KMT2A (0.72) | KMT2AMETAP2RAB9ATSHRHSD17B10 | |
| SCHEMBL2949130 | 0.83 | KMT2A (0.72) | KMT2AMETAP2RAB9ATSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1059722-A | 3-aryl-4 (3H) quinazolinone CCK peptide antagonists and pharmaceutical preparation thereof | LLI LILLY AND CO (US) | 1992-03-25 | — | — | CN | disclosed |