SCHEMBL28850318

SCHEMBL28850318

COc1ccccc1NC(=O)c1cc(N)ccc1N

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.59
METAP2 P50579 1/20 0.57
MAPT P10636 4/20 0.56
RORC P51449 1/20 0.56
RAB9A P51151 5/20 0.56
SMN1; SMN2 Q16637 3/20 0.56
TSHR P16473 2/20 0.56
HSD17B10 Q99714 2/20 0.56
MEN1 O00255 3/20 0.55
LMNA P02545 1/20 0.55
GAA P10253 3/20 0.54
L3MBTL1 Q9Y468 2/20 0.54
POLB P06746 1/20 0.54
RECQL P46063 1/20 0.54
ALDH1A1 P00352 1/20 0.54
TUBB4A P04350 1/20 0.53
TUBB P07437 1/20 0.53
TUBA3C P0DPH7 1/20 0.53
TUBA1B P68363 1/20 0.53
TUBA4A P68366 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17774872 0.88 TUBB4A (0.58) KMT2AMETAP2MAPTRAB9ASMN1; SMN2
SCHEMBL27363382 0.85 KMT2A (0.70) KMT2AMETAP2MAPTRAB9ASMN1; SMN2
SCHEMBL26758015 0.84 RORC (0.78) KMT2AMAPTRORCSMN1; SMN2MEN1
SCHEMBL29963747 0.83 ALDH1A1 (0.55) KMT2AMETAP2MAPTRAB9ASMN1; SMN2
SCHEMBL12368156 0.83 RAB9A (0.63) KMT2AMETAP2MAPTRAB9ASMN1; SMN2
SCHEMBL758414 0.82 MAPT (0.62) KMT2AMETAP2MAPTRAB9ASMN1; SMN2
SCHEMBL17774960 0.81 ALDH1A1 (0.63) KMT2AMAPTRORCRAB9ASMN1; SMN2
SCHEMBL682871 0.80 GAA (0.68) KMT2AMAPTRAB9AMEN1GAA
SCHEMBL17103194 0.79 RORC (0.58) KMT2AMAPTRORCSMN1; SMN2TSHR
SCHEMBL28729469 0.79 KMT2A (0.65) KMT2AMETAP2MAPTRAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115141370-A Polyimide, metal-clad laminate, and circuit board 日铁化学材料株式会社 2022-10-04 CN disclosed
CN-115141560-A Adhesive layer, circuit board using the same, and strip line 日铁化学材料株式会社 2022-10-04 CN disclosed