Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN5A | Q14524 | 3/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.43 |
| ▸ | PNMT | P11086 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.41 |
| ▸ | KIF11 | P52732 | 5/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9015877 | 0.81 | SCN5A (0.49) | SCN5ASCN9APNMTCYP19A1KIF11 | |
| SCHEMBL10643134 | 0.80 | SCN5A (0.44) | SCN5ASCN9APNMTKIF11PKM | |
| SCHEMBL19731492 | 0.79 | CYP19A1 (0.45) | SCN5ASCN9APNMTCYP19A1KIF11 | |
| SCHEMBL6074031 | 0.74 | CYP19A1 (0.47) | SCN5ASCN9ACYP19A1KIF11CHRM3 | |
| Hydrochloric Acid SCHEMBL27601929 | 0.73 | CYP19A1 (0.46) | SCN5ASCN9ACYP19A1KIF11CHRM3 | |
| SCHEMBL9644418 | 0.72 | TDP1 (0.47) | CYP19A1PKMTSHRRECQLPGR | |
| SCHEMBL3356661 | 0.71 | ALDH1A1 (0.50) | SCN5ASCN9APNMTCYP19A1KIF11 | |
| SCHEMBL4968001 | 0.70 | SLC6A2 (0.44) | SCN5ASCN9APNMTCYP19A1KIF11 | |
| SCHEMBL1155523 | 0.70 | CYP19A1 (0.50) | SCN5ASCN9ACYP19A1KIF11CHRM3 | |
| SCHEMBL4294497 | 0.70 | CYP19A1 (0.50) | SCN5ASCN9ACYP19A1KIF11CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1073428-A | Aromatic amino alcohol derivatives having anti-diabetic and anti-obesity properties, their preparation and their therapeutic use | SANKYO CO (JP) | 1993-06-23 | — | — | CN | disclosed |