Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN5A | Q14524 | 3/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.44 |
| ▸ | KIF11 | P52732 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | OGG1 | O15527 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | CCR6 | P51684 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PNMT | P11086 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27363440 | 0.80 | SCN5A (0.43) | SCN5ASCN9AKIF11PKMPNMT | |
| SCHEMBL10643127 | 0.72 | SCN5A (0.48) | SCN5ASCN9AKIF11PKMPARP1 | |
| SCHEMBL9015877 | 0.72 | SCN5A (0.49) | SCN5ASCN9AKIF11PKMPNMT | |
| SCHEMBL19731492 | 0.70 | CYP19A1 (0.45) | SCN5ASCN9AKIF11PARP1CCR6 | |
| SCHEMBL30914002 | 0.68 | KIF11 (0.42) | SCN5ASCN9AKIF11PKMHPGD | |
| SCHEMBL30913940 | 0.68 | KIF11 (0.42) | SCN5ASCN9AKIF11PKMHPGD | |
| SCHEMBL30914073 | 0.68 | KIF11 (0.42) | SCN5ASCN9AKIF11PKMHPGD | |
| SCHEMBL24729465 | 0.68 | ADRA1D (0.47) | HPGDALOX15OGG1PARP1 | |
| SCHEMBL17844752 | 0.68 | ADRA1D (0.47) | HPGDALOX15OGG1PARP1 | |
| SCHEMBL29927069 | 0.68 | ADRA1D (0.47) | HPGDALOX15OGG1PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0278621-A1 | Substituted amine derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1988-08-17 | — | — | EP | disclosed |