Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.41 |
| ▸ | METAP2 | P50579 | 1/20 | 0.41 |
| ▸ | TPMT | P51580 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MYC | P01106 | 1/20 | 0.37 |
| ▸ | TTR | P02766 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | GABRP | O00591 | 1/20 | 0.35 |
| ▸ | GABRD | O14764 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27447318 | 0.90 | KDM4E (0.48) | KDM4ECSNK2A1METAP2TPMTHSD17B10 | |
| SCHEMBL27382937 | 0.83 | TPMT (0.42) | KDM4ETPMTHSD17B10ALDH1A1MYC | |
| SCHEMBL10920134 | 0.82 | KDM4E (0.55) | KDM4ECSNK2A1METAP2TPMTHSD17B10 | |
| SCHEMBL9191019 | 0.81 | KDM4E (0.53) | KDM4ECSNK2A1METAP2TPMTHSD17B10 | |
| SCHEMBL2565863 | 0.80 | CDC25B (0.43) | KDM4EHSD17B10ALDH1A1GAAHPGD | |
| SCHEMBL27452461 | 0.78 | KMT2A (0.36) | KDM4EMETAP2ALDH1A1GAALMNA | |
| SCHEMBL14883883 | 0.77 | KDM4E (0.51) | KDM4ECSNK2A1HSD17B10ALDH1A1HPGD | |
| SCHEMBL8955994 | 0.77 | KDM4E (0.49) | KDM4ECSNK2A1METAP2TPMTHSD17B10 | |
| SCHEMBL6736179 | 0.75 | HSD17B10 (0.55) | KDM4ECSNK2A1TPMTHSD17B10ALDH1A1 | |
| SCHEMBL13517420 | 0.74 | KDM4E (0.46) | KDM4ECSNK2A1METAP2TPMTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1071540-C | Stabilization of aqueous 3-isothiazolone solutions | ROHM & HAAS (US) | 2001-09-26 | — | — | CN | disclosed |
| CN-1140542-A | Stabilization of aqueous 3-isothiazolone solutions | ROHM & HAAS (US) | 1997-01-22 | — | — | CN | disclosed |