Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.50 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.43 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | METAP2 | P50579 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.40 |
| ▸ | TPMT | P51580 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9191019 | 0.98 | KDM4E (0.53) | KDM4EHSD17B10NOTUMCSNK2A1ALDH1A1 | |
| SCHEMBL6736179 | 0.90 | HSD17B10 (0.55) | KDM4EHSD17B10NOTUMCSNK2A1ALDH1A1 | |
| SCHEMBL8431119 | 0.84 | KDM4E (0.41) | KDM4EALDH1A1HPGDACHEPKM | |
| SCHEMBL7820121 | 0.84 | HSD17B10 (0.50) | KDM4EHSD17B10NOTUMCSNK2A1ALDH1A1 | |
| SCHEMBL10355461 | 0.82 | ACHE (0.59) | KDM4EHSD17B10ALDH1A1HPGDMAPT | |
| SCHEMBL27801015 | 0.82 | TPMT (0.49) | KDM4EHSD17B10NOTUMALDH1A1HPGD | |
| SCHEMBL12345885 | 0.82 | KDM4E (0.46) | KDM4EHSD17B10ALDH1A1HPGDMAPT | |
| SCHEMBL27363495 | 0.82 | KDM4E (0.53) | KDM4EHSD17B10NOTUMCSNK2A1ALDH1A1 | |
| SCHEMBL19100974 | 0.82 | HSD17B10 (0.49) | KDM4EHSD17B10NOTUMALDH1A1HPGD | |
| SCHEMBL12505480 | 0.82 | NNMT (0.50) | KDM4EALDH1A1ACHEPKMPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10167269-B2 | Cockroach attraction-aggregation substance, cockroach aggregation attractant and cockroach controlling agent | KYOTO UNIVERSITY (JP) | 2019-01-01 | — | — | US | disclosed |
| US-20160326129-A1 | COCKROACH ATTRACTION-AGGREGATION SUBSTANCE, COCKROACH AGGREGATION ATTRACTANT AND COCKROACH CONTROLLING AGENT | KYOTO UNIVERSITY (JP) | 2016-11-10 | — | — | US | disclosed |
| US-8354439-B2 | Agent for inhibition of cytokine production and agent for inhibition of cell adhesion | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2013-01-15 | — | — | US | disclosed |
| US-20070238758-A1 | Agent for inhibition of cytokine production and agent for inhibition of cell adhesion | OTSUKA PHARMACEUTICAL CO., LTD. | 2007-10-11 | — | — | US | disclosed |
| US-20070105911-A1 | Agent for inhibition of cytokine production and agent for inhibition of cell adhesion | CHIHIRO MASATOSHI | 2007-05-10 | — | — | US | disclosed |
| EP-0091402-B1 | CHROMENOAZAINDOLIZINES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN PRESSURE OR HEAT SENSITIVE RECORDING MATERIALS | CIBA-GEIGY AG (CH) | 1986-02-26 | — | — | EP | disclosed |
| US-4506073-A | Chromenoazaindolizine compounds | CIBA-GEIGY CORPORATION (US) | 1985-03-19 | — | — | US | disclosed |
| EP-0091402-A2 | Chromenoazaindolizines, process for their preparation and their use in pressure or heat sensitive recording materials | CIBA-GEIGY AG (CH) | 1983-10-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070238758-A1 | Agent for inhibition of cytokine production and agent for inhibition of cell adhesion | IL2, IL1RN, SELL | KDM4E 3406/4885HSD17B10 2019/4885NOTUM 2970/4885 |
| US-20070105911-A1 | Agent for inhibition of cytokine production and agent for inhibition of cell adhesion | IL2, IL1RN, SELL | KDM4E 3397/4885HSD17B10 2064/4885NOTUM 3052/4885 |
| US-20160326129-A1 | COCKROACH ATTRACTION-AGGREGATION SUBSTANCE, COCKROACH AGGREGATION ATTRACTANT AND COCKROACH CONTROLLING AGENT | ACHE, STOM, NAPA | KDM4E 4790/4885HSD17B10 4408/4885NOTUM 785/4885 |
| US-10167269-B2 | Cockroach attraction-aggregation substance, cockroach aggregation attractant and cockroach controlling agent | ACHE, STOM, NAPA | KDM4E 4790/4885HSD17B10 4408/4885NOTUM 785/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.