SCHEMBL8955994

SCHEMBL8955994

Cc1cc(C)c(OC(C)(C)C)c(C(=O)O)c1.[Zn]

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.49
CSNK2A1 P68400 1/20 0.38
METAP2 P50579 1/20 0.38
ALDH1A1 P00352 5/20 0.37
L3MBTL1 Q9Y468 3/20 0.37
TPMT P51580 1/20 0.35
HSD17B10 Q99714 3/20 0.34
MYC P01106 1/20 0.34
RXRB P28702 1/20 0.34
TTR P02766 1/20 0.34
GAA P10253 2/20 0.34
LMNA P02545 1/20 0.34
HPGD P15428 2/20 0.33
LCK P06239 1/20 0.33
NOTUM Q6P988 1/20 0.33
MEN1 O00255 1/20 0.33
POLB P06746 1/20 0.33
MAPT P10636 1/20 0.33
PKM P14618 1/20 0.33
APEX1 P27695 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Zinc Ion SCHEMBL8761476 0.81 KDM4E (0.36) KDM4EALDH1A1L3MBTL1MAPT
SCHEMBL9191019 0.80 KDM4E (0.53) KDM4ECSNK2A1METAP2ALDH1A1TPMT
SCHEMBL10920134 0.78 KDM4E (0.55) KDM4ECSNK2A1METAP2ALDH1A1TPMT
SCHEMBL19047018 0.77 MAPT (0.37) KDM4EALDH1A1GAALMNAPOLB
SCHEMBL27363495 0.77 KDM4E (0.53) KDM4ECSNK2A1METAP2ALDH1A1TPMT
SCHEMBL17648738 0.74 POLB (0.44) KDM4EALDH1A1L3MBTL1RXRBGAA
SCHEMBL14883883 0.72 KDM4E (0.51) KDM4ECSNK2A1ALDH1A1HSD17B10HPGD
SCHEMBL6908359 0.71 KDM4E (0.61) KDM4ECSNK2A1METAP2ALDH1A1TPMT
SCHEMBL6736179 0.71 HSD17B10 (0.55) KDM4ECSNK2A1ALDH1A1TPMTHSD17B10
SCHEMBL14988854 0.71 PPARA (0.55) MEN1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0360014-B1 Photosensitive material and image forming method using same CANON KK (JP) 1996-01-03 EP disclosed
EP-0412851-B1 Photosensitive member and multi-color image forming method CANON KK (JP) 1995-06-14 EP disclosed
US-5415974-A Silver halide, organic silver salt, polymerizable compound, heat-diffusing dye CANON KABUSHIKI KAISHA (JP) 1995-05-16 US disclosed
US-5266441-A Heat diffusible coloring compound, polymerizable binder CANON KABUSHIKI KAISHA (JP) 1993-11-30 US disclosed
US-5073791-A IMAGE FORMING DEVICE CANON KABUSHIKI KAISHA (JP) 1991-12-17 US disclosed
US-5021321-A Photothermography; antifogging agents; contrast; lamination of matrix of silver salts and reducing agent and dispersed particles of dye, polymer precursor and photoinitiator CANON KABUSHIKI KAISHA (JP) 1991-06-04 US disclosed
EP-0412851-A2 Photosensitive member and multi-color image forming method CANON KABUSHIKI KAISHA (JP) 1991-02-13 EP disclosed
EP-0411839-A2 Image forming medium and image forming method CANON KABUSHIKI KAISHA (JP) 1991-02-06 EP disclosed
EP-0410803-A2 Image forming device CANON KABUSHIKI KAISHA (JP) 1991-01-30 EP disclosed
EP-0360014-A1 Photosensitive material and image forming method using same CANON KABUSHIKI KAISHA (JP) 1990-03-28 EP disclosed