Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 known ✓ | P31645 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 5/20 | 0.47 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.47 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.47 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.47 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Azelaic Acid SCHEMBL28307577 | 0.88 | ABCC4 (0.61) | ALOX5SMN1; SMN2LMNAABCC4MAPT | |
| SCHEMBL131849 | 0.85 | — | — | |
| Diallyl Sulfide SCHEMBL27447448 | 0.84 | ALOX5 (0.58) | ALOX5SMN1; SMN2LMNAABCC4MAPT | |
| SCHEMBL9015057 | 0.83 | ALOX5 (0.44) | ALOX5SMN1; SMN2LMNAABCC4MAPT | |
| Diallyl Sulfide SCHEMBL27287761 | 0.82 | ALOX5 (0.55) | ALOX5SMN1; SMN2LMNAABCC4MAPT | |
| SCHEMBL4541215 | 0.81 | TSHR (0.59) | ALOX5SMN1; SMN2LMNAABCC4MAPT | |
| Diallyl Sulfide SCHEMBL23070593 | 0.81 | ALOX5 (0.61) | ALOX5SMN1; SMN2LMNAABCC4MAPT | |
| SCHEMBL10503956 | 0.80 | TSHR (0.52) | ALOX5SMN1; SMN2LMNAABCC4MAPT | |
| SCHEMBL173833 | 0.79 | — | — | |
| SCHEMBL28912299 | 0.78 | ABCC4 (0.45) | LMNAEGLN1ALKBH5SUCNR1ABCC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105404104-A | TONER FOR DEVELOPING ELECTROSTATIC LATENT IMAGE AND PROCESS FOR PRODUCING THE SAME | KONICA MINOLTA INC | 2016-03-16 | — | — | CN | disclosed |
| CN-100586964-C | Process for the polymerization of olefins in the presence of an anti-fouling agent | TOTAL PETROCHEMICALS RES FELUY | 2010-02-03 | — | — | CN | disclosed |
| CN-1918198-A | Olefin polymerisation process in the presence of an anti-fouling agent | TOTAL PETROCHEMICALS RES FELUY (BE) | 2007-02-21 | — | — | CN | disclosed |
| CN-1072689-A | Reduce the expansile method of latex | ROHM & HAAS (US) | 1993-06-02 | — | — | CN | disclosed |