Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | PPARG | P37231 | 3/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.42 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | TERT | O14746 | 3/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.33 |
| ▸ | BLM | P54132 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinic Acid SCHEMBL27363512 | 0.83 | ALOX5 (0.58) | ALOX5SMN1; SMN2TBXA2RMAPTALDH1A1 | |
| Azelaic Acid SCHEMBL28307577 | 0.77 | ABCC4 (0.61) | ALOX5SMN1; SMN2MAPTPPARGFFAR1 | |
| SCHEMBL10823289 | 0.76 | MAPT (0.54) | TBXA2RMAPTPPARGCYP19A1FFAR1 | |
| SCHEMBL10823290 | 0.76 | MAPT (0.54) | TBXA2RMAPTPPARGCYP19A1FFAR1 | |
| SCHEMBL176452 | 0.75 | PPARG (0.64) | TBXA2RMAPTPPARGCYP19A1FFAR1 | |
| SCHEMBL176453 | 0.75 | PPARG (0.64) | TBXA2RMAPTPPARGCYP19A1FFAR1 | |
| SCHEMBL2540034 | 0.75 | PPARG (0.64) | TBXA2RMAPTPPARGCYP19A1FFAR1 | |
| SCHEMBL2575705 | 0.74 | ALDH1A1 (0.59) | MAPTPPARGCYP19A1FFAR1ALDH1A1 | |
| SCHEMBL8017585 | 0.74 | ALDH1A1 (0.59) | MAPTPPARGCYP19A1FFAR1ALDH1A1 | |
| SCHEMBL2575707 | 0.74 | ALDH1A1 (0.59) | MAPTPPARGCYP19A1FFAR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0745071-A1 | 4-AMINO 6-SUBSTITUTED MYCOPHENOLIC ACID AND DERIVATIVES WITH IMMUNOSUPPRESSIVE ACTIVITY | SYNTEX (U.S.A.) INC. (US) | 1996-12-04 | — | — | EP | disclosed |
| EP-0745075-A1 | 6-SUBSTITUTED MYCOPHENOLIC AND DERIVATIVES WITH IMMUNOSUPPRESSIVE ACTIVITY | SYNTEX (U.S.A.) INC. (US) | 1996-12-04 | — | — | EP | disclosed |