Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.45 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.43 |
| ▸ | JAK1 | P23458 | 2/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | JAK3 | P52333 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.40 |
| ▸ | GSK3B | P49841 | 2/20 | 0.40 |
| ▸ | CCR6 | P51684 | 2/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.40 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.40 |
| ▸ | IKBKB | O14920 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | CLK2 | P49760 | 1/20 | 0.39 |
| ▸ | CLK3 | P49761 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19957585 | 0.91 | HRH4 (0.44) | SYKHRH4HCAR3JAK1JAK2 | |
| SCHEMBL27680946 | 0.85 | HCAR3 (0.56) | HCAR3CCR6 | |
| SCHEMBL2709790 | 0.85 | HCAR3 (0.56) | HCAR3CCR6 | |
| SCHEMBL15986824 | 0.83 | HRH4 (0.46) | SYKHRH4POLBHCAR3JAK1 | |
| SCHEMBL17409788 | 0.83 | CCR6 (0.55) | SYKHRH4POLBHCAR3JAK1 | |
| SCHEMBL18307123 | 0.80 | HCAR3 (0.57) | HCAR3 | |
| SCHEMBL15247187 | 0.79 | SYK (0.43) | SYKHRH4POLBHCAR3JAK1 | |
| SCHEMBL17403568 | 0.79 | CCR6 (0.51) | SYKHRH4POLBHCAR3JAK1 | |
| SCHEMBL14147328 | 0.78 | CYP11B1 (0.47) | SYKHRH4POLBHCAR3JAK1 | |
| SCHEMBL16730436 | 0.78 | CCR6 (0.58) | SYKCCR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024054591-A1 | RAPIDLY ACCELERATED FIBROSARCOMA (RAF) DEGRADING COMPOUNDS AND ASSOCIATED METHODS OF USE | ARVINAS OPERATIONS, INC. (US) | 2024-03-14 | — | — | WO | disclosed |