Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKAA1 | Q13131 | 14/20 | 0.57 |
| ▸ | PRKAG1 | P54619 | 13/20 | 0.57 |
| ▸ | PRKAB1 | Q9Y478 | 13/20 | 0.57 |
| ▸ | PRKAB2 | O43741 | 12/20 | 0.54 |
| ▸ | PRKAA2 | P54646 | 12/20 | 0.54 |
| ▸ | PRKAG3 | Q9UGI9 | 12/20 | 0.54 |
| ▸ | PRKAG2 | Q9UGJ0 | 12/20 | 0.54 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.44 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | CDK1 | P06493 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | MARK3 | P27448 | 1/20 | 0.43 |
| ▸ | CLK2 | P49760 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27777072 | 0.89 | PRKAG1 (0.47) | PRKAA1PRKAG1PRKAB1PRKAB2PRKAA2 | |
| SCHEMBL1963808 | 0.88 | PRKAG1 (0.53) | PRKAA1PRKAG1PRKAB1PRKAB2PRKAA2 | |
| SCHEMBL1963540 | 0.88 | PRKAG1 (0.53) | PRKAA1PRKAG1PRKAB1PRKAB2PRKAA2 | |
| SCHEMBL12479871 | 0.87 | KDM4E (0.44) | PRKAA1PRKAG1PRKAB1PRKAB2PRKAA2 | |
| SCHEMBL1964504 | 0.83 | PRKAG1 (0.48) | PRKAA1PRKAG1PRKAB1PRKAB2PRKAA2 | |
| SCHEMBL14915843 | 0.82 | PRKAG1 (0.46) | PRKAA1PRKAG1PRKAB1PRKAB2PRKAA2 | |
| SCHEMBL10569944 | 0.81 | KDM4E (0.58) | PRKAA1KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL7809574 | 0.80 | KDM4E (0.59) | KDM4EALDH1A1HPGDSMN1; SMN2GAA | |
| SCHEMBL13931932 | 0.79 | TUBB1 (0.46) | — | |
| SCHEMBL13632234 | 0.79 | PRKAG1 (0.53) | PRKAA1PRKAG1PRKAB1PRKAB2PRKAA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1067998-C | Hydrate for medicinal use | DAIICHI PHARMACEUDTICAL CO LTD (JP) | 2001-07-04 | — | — | CN | disclosed |
| CN-1171786-A | Hydrate for medicinal use | DAIICHI SEIYAKU CO (JP) | 1998-01-28 | — | — | CN | disclosed |
| CN-1100301-A | Drug for neuroprotection | DAIICHI SEIYAKU CO (JP) | 1995-03-22 | — | — | CN | disclosed |