Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC1 | P33527 | 1/20 | 0.46 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.44 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.44 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.44 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.39 |
| ▸ | CCR2 | P41597 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2647640 | 0.84 | CACNA1F (0.44) | CACNA1FCACNA1DCACNA1SCACNA1CGAA | |
| SCHEMBL9312804 | 0.78 | ABCC1 (0.65) | ABCC1CACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL5452620 | 0.76 | ALDH1A1 (0.41) | ABCC1CACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL10830868 | 0.74 | ABCC1 (0.52) | ABCC1CACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL27310185 | 0.73 | CACNA1F (0.52) | ABCC1CACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL27365132 | 0.72 | CACNA1F (0.38) | CACNA1FCACNA1DCACNA1SCACNA1CGAA | |
| SCHEMBL8562368 | 0.71 | HPGD (0.46) | ABCC1CACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL27360297 | 0.71 | IDO1 (0.37) | PTPN1NPSR1CACNA1B | |
| SCHEMBL8949694 | 0.70 | CACNA1F (0.64) | CACNA1FCACNA1DCACNA1SCACNA1CHPGD | |
| SCHEMBL9217592 | 0.70 | NPSR1 (0.69) | ABCC1HPGDKDM4EGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1274719-A | Process for preparation of substituted pyridine compound | BAYER AG (DE) | 2000-11-29 | — | — | CN | disclosed |
| CN-1055684-C | Process for preparing substituted pyridine compounds | BAYER AG (DE) | 2000-08-23 | — | — | CN | disclosed |