Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC1 | P33527 | 1/20 | 0.65 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.53 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.53 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.53 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.53 |
| ▸ | CACNA1B | Q00975 | 10/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7817406 | 0.86 | ABCC1 (0.65) | ABCC1CACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL27541931 | 0.85 | CACNA1B (0.49) | ABCC1CACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL30932230 | 0.84 | ALDH1A1 (0.64) | ABCC1CACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL7410687 | 0.83 | CACNA1B (0.61) | CACNA1FCACNA1DCACNA1SCACNA1CCACNA1B | |
| SCHEMBL8949674 | 0.82 | CACNA1F (0.53) | ABCC1CACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL4789805 | 0.82 | LMNA (0.48) | ABCC1CACNA1BKDM4EHPGDALDH1A1 | |
| SCHEMBL10895180 | 0.81 | CACNA1F (0.76) | ABCC1CACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL4503644 | 0.80 | CACNA1B (0.65) | CACNA1B | |
| SCHEMBL27517088 | 0.79 | KDM4E (0.68) | ABCC1CACNA1DCACNA1BKDM4EHPGD | |
| SCHEMBL7484985 | 0.79 | CACNA1B (0.44) | ABCC1CACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1261348-A | Dihydropyridine derivatives | AJINOMTO CO INC (JP) | 2000-07-26 | — | — | CN | disclosed |
| US-5328931-A | Nervous sytem disorders, cognition activators | BAYER AKTIENGESELLSCHAFT (DE) | 1994-07-12 | — | — | US | disclosed |