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Sugi Predict / Compounds / SCHEMBL27363898

SCHEMBL27363898

SCHEMBL27363898

c1ccc(-n2c3ccccc3c3cc(-c4ccc5c(c4)c4cc6ccccc6cc4n5-c4ccc(-c5nc(-c6cccc7oc8ccccc8c67)c6oc7ccc(-c8ccc9oc%10ccccc%10c9c8)cc7c6n5)c5oc6ccccc6c45)ccc32)cc1

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ PIM1 P11309 1/20 0.32
▸ CSNK2A2 P19784 1/20 0.32
▸ CSNK2B P67870 1/20 0.32
▸ PIM3 Q86V86 1/20 0.32
▸ PIM2 Q9P1W9 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27363873 0.93 PIM1 (0.37) PIM1CSNK2A2CSNK2BPIM3PIM2
SCHEMBL27363884 0.92 PIM1 (0.35) PIM1CSNK2A2CSNK2BPIM3PIM2
SCHEMBL27363875 0.91 PIM1 (0.36) PIM1CSNK2A2CSNK2BPIM3PIM2
SCHEMBL27363952 0.90 PIM1 (0.37) PIM1CSNK2A2CSNK2BPIM3PIM2
SCHEMBL27364125 0.88 ALOX5 (0.36) PIM1CSNK2A2CSNK2BPIM3PIM2
SCHEMBL27363878 0.88 PIM1 (0.39) PIM1CSNK2A2CSNK2BPIM3PIM2
SCHEMBL27364036 0.88 ALDH1A1 (0.34) PIM1CSNK2A2CSNK2BPIM3PIM2
SCHEMBL27363934 0.88 PIM1 (0.36) PIM1CSNK2A2CSNK2BPIM3PIM2
SCHEMBL20030261 0.88 PIM1 (0.36) PIM1CSNK2A2CSNK2BPIM3PIM2
SCHEMBL27363959 0.88 PIM1 (0.36) PIM1CSNK2A2CSNK2BPIM3PIM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240215277-A1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2024-06-27 — — US disclosed
US-20240215277-A1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2024-06-27 — — US disclosed