Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 1/20 | 0.48 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | KCNN4 | O15554 | 5/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.43 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28645883 | 0.85 | ALDH1A1 (0.56) | MAPTALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL9987053 | 0.82 | BCAT2 (0.46) | METAP2BCAT2MAPTALDH1A1KDM4E | |
| SCHEMBL7895597 | 0.81 | BCAT2 (0.44) | METAP2BCAT2MAPTALDH1A1KDM4E | |
| SCHEMBL5242160 | 0.81 | MAPT (0.50) | METAP2BCAT2MAPTALDH1A1KDM4E | |
| SCHEMBL27811836 | 0.80 | ALDH1A1 (0.45) | MAPTALDH1A1KDM4EHPGDTSHR | |
| SCHEMBL27752377 | 0.79 | KCNN4 (0.45) | METAP2BCAT2MAPTALDH1A1KDM4E | |
| SCHEMBL1004509 | 0.78 | ALDH1A1 (0.48) | METAP2BCAT2MAPTALDH1A1KDM4E | |
| SCHEMBL9986711 | 0.77 | MAPT (0.42) | METAP2BCAT2MAPTALDH1A1KDM4E | |
| SCHEMBL31186401 | 0.76 | ALDH1A1 (0.62) | MAPTALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL8402762 | 0.76 | ALDH1A1 (0.62) | MAPTALDH1A1KDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1060778-C | Cephalosporin derivatives | HOFFMANN LA ROCHE (CH) | 2001-01-17 | — | — | CN | disclosed |