Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDR1 | Q08345 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 3/20 | 0.34 |
| ▸ | CCR3 | P51677 | 3/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | XDH | P47989 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.32 |
| ▸ | WDR5 | P61964 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17057147 | 0.80 | DDR1 (0.41) | DDR1P2RX7HRH1CCR3KCNH2 | |
| SCHEMBL214467 | 0.78 | DDR1 (0.42) | DDR1P2RX7HRH1CCR3KCNH2 | |
| SCHEMBL30491310 | 0.78 | TSHR (0.37) | DDR1P2RX7HRH1CCR3KCNH2 | |
| Hydrochloric Acid SCHEMBL29715665 | 0.77 | DDR1 (0.41) | DDR1P2RX7HRH1CCR3KCNH2 | |
| SCHEMBL30147962 | 0.77 | DDR1 (0.41) | DDR1P2RX7HRH1CCR3KCNH2 | |
| SCHEMBL23853474 | 0.77 | DDR1 (0.39) | DDR1P2RX7HRH1CCR3KCNH2 | |
| SCHEMBL20304370 | 0.77 | PLK4 (0.42) | DDR1P2RX7TSHRXDHGAA | |
| SCHEMBL353369 | 0.76 | DDR1 (0.47) | DDR1P2RX7HRH1CCR3KCNH2 | |
| SCHEMBL29106671 | 0.76 | TSHR (0.57) | DDR1P2RX7TSHRSMN1; SMN2GAA | |
| SCHEMBL25017479 | 0.73 | TSHR (0.58) | TSHRGAAAHRHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024026483-A2 | CDK2 INHIBITORS AND METHODS OF USING THE SAME | CEDILLA THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |