Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 3/20 | 0.34 |
| ▸ | GSK3B | P49841 | 2/20 | 0.33 |
| ▸ | ALPL | P05186 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.32 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | PLG | P00747 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23855383 | 0.81 | ALDH1A1 (0.40) | ALPLLMNAMAPK1MEN1KMT2A | |
| SCHEMBL27316081 | 0.80 | MAPK1 (0.34) | HCAR3GSK3BALPLCA12MAPK1 | |
| SCHEMBL5064411 | 0.79 | ALPL (0.51) | ALPLLMNAMEN1KMT2AKDM4E | |
| SCHEMBL3452780 | 0.78 | DYRK1A (0.34) | ALPLCA12MAPK1 | |
| SCHEMBL1498674 | 0.78 | ALPL (0.46) | HCAR3ALPLCA12CA9HCAR2 | |
| SCHEMBL2790797 | 0.77 | PLA2G10 (0.41) | ALPLKMT2A | |
| Hydrochloric Acid SCHEMBL31067451 | 0.77 | ALPL (0.45) | HCAR3ALPLCA12CA9HCAR2 | |
| SCHEMBL1498628 | 0.76 | MAPK1 (0.59) | ALPLLMNAMAPK1 | |
| SCHEMBL16629835 | 0.76 | CHEK1 (0.51) | GSK3BALPLBRD4MAPK1KDM4E | |
| Hydrochloric Acid SCHEMBL31067680 | 0.75 | PLA2G10 (0.40) | ALPLKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024026483-A2 | CDK2 INHIBITORS AND METHODS OF USING THE SAME | CEDILLA THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |