Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 9/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | TLR4 | O00206 | 1/20 | 0.40 |
| ▸ | TLR2 | O60603 | 1/20 | 0.40 |
| ▸ | G6PD | P11413 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Chlorobenzene SCHEMBL28065157 | 0.80 | FBP1 (0.50) | FBP1HSP90AA1TSHRALDH1A1MAPT | |
| Chlorobenzene SCHEMBL11291900 | 0.78 | TSHR (0.58) | FBP1TSHRALDH1A1G6PDTDP1 | |
| Chlorobenzene SCHEMBL27463303 | 0.76 | TSHR (0.55) | FBP1TSHRALDH1A1G6PDTDP1 | |
| SCHEMBL15930033 | 0.75 | — | — | |
| SCHEMBL27956 | 0.75 | — | — | |
| SCHEMBL406091 | 0.75 | — | — | |
| Chlorobenzene SCHEMBL4617117 | 0.73 | TSHR (0.58) | FBP1TSHRALDH1A1MAPTG6PD | |
| Chlorobenzene SCHEMBL27318453 | 0.73 | TSHR (0.65) | HSP90AA1TSHRALDH1A1MAPTMEN1 | |
| Chlorobenzene SCHEMBL28326334 | 0.71 | TSHR (0.61) | HSP90AA1TSHRALDH1A1MAPTMEN1 | |
| Chlorobenzene SCHEMBL28085392 | 0.71 | TSHR (0.61) | HSP90AA1TSHRALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1058707-C | Process for synthesis of d1-trans-4-phenyl-5-0-chlorobenzyl-pyrrolidone-2 | KUNMING PLANTS INST CHINA ACAD (CN) | 2000-11-22 | — | — | CN | disclosed |
| CN-1191218-A | Process for synthesis of d1-trans-4-phenyl-5-0-chlorobenzyl-pyrrolidone-2 | KUNMING PLANTS INST CHINESE AC (CN) | 1998-08-26 | — | — | CN | disclosed |