SCHEMBL2736459

SCHEMBL2736459

NCC1OC(O)C(N)C(O)C1O

nearest known ligand 0.45

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ LRAT O95237 2/20 0.45
▸ LMNA P02545 1/20 0.39
▸ KDM4E B2RXH2 1/20 0.39
▸ ALOX15 P16050 1/20 0.39
▸ MEN1 O00255 2/20 0.38
▸ TRPV1 Q8NER1 1/20 0.38
▸ TSHR P16473 2/20 0.37
▸ HSD17B10 Q99714 1/20 0.37
▸ GJA1 P17302 1/20 0.36
▸ GJB2 P29033 1/20 0.36
▸ CYP2C9 P11712 1/20 0.36
▸ KMT2A Q03164 1/20 0.36
▸ ALDH1A1 P00352 1/20 0.36
▸ GBA1 P04062 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8218250 1.00 LRAT (0.45) LRATLMNAKDM4EALOX15MEN1
SCHEMBL11289960 1.00 LRAT (0.45) LRATLMNAKDM4EALOX15MEN1
SCHEMBL11505783 1.00 LRAT (0.45) LRATLMNAKDM4EALOX15MEN1
SCHEMBL10870794 1.00 LRAT (0.45) LRATLMNAKDM4EALOX15MEN1
SCHEMBL10870801 1.00 LRAT (0.45) LRATLMNAKDM4EALOX15MEN1
SCHEMBL23231183 1.00 LRAT (0.45) LRATLMNAKDM4EALOX15MEN1
SCHEMBL16181597 1.00 LRAT (0.45) LRATLMNAKDM4EALOX15MEN1
SCHEMBL12685581 1.00 LRAT (0.45) LRATLMNAKDM4EALOX15MEN1
SCHEMBL21454659 1.00 LRAT (0.45) LRATLMNAKDM4EALOX15MEN1
SCHEMBL8218251 1.00 LRAT (0.45) LRATLMNAKDM4EALOX15MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9468595-B2 Acrylamide derivatives EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2016-10-18 — — US disclosed
US-9238774-B2 Soil fixation, dust suppression and water retention EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2016-01-19 — — US disclosed
US-9238774-B2 Soil fixation, dust suppression and water retention EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2016-01-19 — — US disclosed
US-9238774-B2 Soil fixation, dust suppression and water retention EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2016-01-19 — — US disclosed
US-9212245-B2 High performance acrylamide adhesives EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2015-12-15 — — US disclosed
US-9212245-B2 High performance acrylamide adhesives EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2015-12-15 — — US disclosed
US-9212245-B2 High performance acrylamide adhesives EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2015-12-15 — — US disclosed
US-20140178344-A1 ACRYLAMIDE HYDROGELS FOR TISSUE ENGINEERING EMPIRE TECHNOLOGY DEVELOPMENT LLC 2014-06-26 — — US disclosed
US-20140178344-A1 ACRYLAMIDE HYDROGELS FOR TISSUE ENGINEERING EMPIRE TECHNOLOGY DEVELOPMENT LLC 2014-06-26 — — US disclosed
US-20140178344-A1 ACRYLAMIDE HYDROGELS FOR TISSUE ENGINEERING EMPIRE TECHNOLOGY DEVELOPMENT LLC 2014-06-26 — — US disclosed
US-20140155563-A1 HIGH PERFORMANCE ACRYLAMIDE ADHESIVES EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2014-06-05 — — US disclosed
US-20140155563-A1 HIGH PERFORMANCE ACRYLAMIDE ADHESIVES EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2014-06-05 — — US disclosed
US-20140155563-A1 HIGH PERFORMANCE ACRYLAMIDE ADHESIVES EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2014-06-05 — — US disclosed
WO-2014070194-A1 SOIL FIXATION, DUST SUPPRESSION AND WATER RETENTION EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2014-05-08 — — WO disclosed
US-20140126966-A1 SOIL FIXATION, DUST SUPPRESSION AND WATER RETENTION CRESTLINE DIRECT FINANCE, L.P. 2014-05-08 — — US disclosed
US-20140126966-A1 SOIL FIXATION, DUST SUPPRESSION AND WATER RETENTION CRESTLINE DIRECT FINANCE, L.P. 2014-05-08 — — US disclosed
US-20140126966-A1 SOIL FIXATION, DUST SUPPRESSION AND WATER RETENTION CRESTLINE DIRECT FINANCE, L.P. 2014-05-08 — — US disclosed
US-8088626-B2 Chiral selectors for separating enantiomers of a compound University Joseph Fourier (Grenoble 1) (FR) 2012-01-03 — — US disclosed
US-20100144045-A1 CHIRAL SELECTORS FOR SEPARATING ENANTIOMERS OF A COMPOUND UNIVERISTE JOSEPH FOURIER (GRENOBLE 1) (FR) 2010-06-10 — — US disclosed
WO-2008132340-A2 CHIRAL SELECTORS FOR SEPARATING ENANTIOMERS OF A COMPOUND UNIVERSITE JOSEPH FOURIER (GRENOBLE 1) (FR) 2008-11-06 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100144045-A1 CHIRAL SELECTORS FOR SEPARATING ENANTIOMERS OF A COMPOUND CD2, CD22, CA2 LRAT 2404/4885LMNA 4394/4885KDM4E 2950/4885
US-20140155563-A1 HIGH PERFORMANCE ACRYLAMIDE ADHESIVES ITGAM, WASF2, EPCAM LRAT 1860/4885LMNA 3918/4885KDM4E 3147/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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