Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PPIA | P62937 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4403626 | 0.81 | SMN1; SMN2 (0.61) | HSD17B10NPC1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL8068953 | 0.80 | ALOX15 (0.47) | HSD17B10ALOX15NPC1HPGDRAB9A | |
| SCHEMBL4279981 | 0.79 | HSD17B10 (0.61) | HSD17B10NPC1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL1810999 | 0.78 | SMN1; SMN2 (0.55) | HSD17B10NPC1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL8409709 | 0.78 | HSD17B10 (0.47) | HSD17B10NPC1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL340393 | 0.78 | SMN1; SMN2 (0.72) | NPC1HPGDRAB9ASMN1; SMN2KDM4E | |
| SCHEMBL8601204 | 0.78 | CCR5 (0.45) | HPGDALDH1A1 | |
| SCHEMBL13440181 | 0.75 | FFAR4 (0.58) | NPC1HPGDRAB9ASMN1; SMN2PPIA | |
| SCHEMBL18031245 | 0.75 | NPC1 (0.54) | PDE4BHSD17B10NPC1HPGDRAB9A | |
| SCHEMBL15517564 | 0.75 | SMN1; SMN2 (0.54) | HSD17B10NPC1HPGDRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1068879-C | Dihydrobenzofuranes | BYK GULDEN LOMBERY CHEM FAB GM (DE) | 2001-07-25 | — | — | CN | disclosed |
| CN-1159804-A | Dihydrobenzofuranes | BYK GULDEN LOMBERG CHEM FAB (DE) | 1997-09-17 | — | — | CN | disclosed |