Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | FLT3 | P36888 | 1/20 | 0.44 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NQO2 | P16083 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.32 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30594656 | 1.00 | ALDH1A1 (0.52) | ALDH1A1NPC1RAB9APDGFRBSMN1; SMN2 | |
| SCHEMBL12086507 | 0.79 | ALDH1A1 (0.46) | ALDH1A1NPC1RAB9ASMN1; SMN2CYP1A2 | |
| SCHEMBL1401306 | 0.79 | ALDH1A1 (0.49) | ALDH1A1PDGFRBSMN1; SMN2PDGFRANQO2 | |
| SCHEMBL6187822 | 0.74 | PAX8 (0.47) | ALDH1A1NPC1RAB9APDGFRBSMN1; SMN2 | |
| SCHEMBL9798625 | 0.74 | ALDH1A1 (0.36) | ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL29092402 | 0.73 | SMN1; SMN2 (0.42) | ALDH1A1NPC1RAB9APDGFRBSMN1; SMN2 | |
| SCHEMBL30594658 | 0.73 | SMN1; SMN2 (0.42) | ALDH1A1NPC1RAB9APDGFRBSMN1; SMN2 | |
| SCHEMBL10974039 | 0.72 | CYP1A2 (0.49) | ALDH1A1NPC1RAB9ASMN1; SMN2CYP1A2 | |
| SCHEMBL28946507 | 0.72 | APP (0.46) | ALDH1A1PDGFRBPDGFRACYP1A2KDM4E | |
| SCHEMBL28964184 | 0.72 | APP (0.46) | ALDH1A1PDGFRBKDRPDGFRACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115028624-A | Quinoxaline framework NN oxazoline ligand and synthetic method and application thereof | 上海师范大学 | 2022-09-09 | — | — | CN | claimed |
| CN-115028624-B | Quinoxaline skeleton NN oxazoline ligand and synthetic method and application thereof | 上海师范大学 | 2023-10-27 | — | — | CN | disclosed |
| CN-115028624-A | Quinoxaline framework NN oxazoline ligand and synthetic method and application thereof | 上海师范大学 | 2022-09-09 | — | — | CN | disclosed |
| CN-1065744-C | Treatment of diseases associated with platelet derived growth factor such as cancer | SUGEN INC (US) | 2001-05-16 | — | — | CN | disclosed |
| CN-1128496-A | Treatment of platelet derived growth factor related disorders such as cancers using inhibitors of platelet derived growth receptor | SUGEN INC (US) | 1996-08-07 | — | — | CN | disclosed |