Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | PDE4A | P27815 | 1/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.45 |
| ▸ | HTR3B | O95264 | 1/20 | 0.45 |
| ▸ | HTR3A | P46098 | 1/20 | 0.45 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.45 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.45 |
| ▸ | EDNRB | P24530 | 1/20 | 0.45 |
| ▸ | PRKCB | P05771 | 2/20 | 0.44 |
| ▸ | GSK3B | P49841 | 2/20 | 0.44 |
| ▸ | TNF | P01375 | 1/20 | 0.43 |
| ▸ | LITAF | Q99732 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27392324 | 0.89 | POLB (0.43) | CNR1CNR2EDNRBPRKCBGSK3B | |
| SCHEMBL27389831 | 0.87 | RXFP1 (0.49) | EDNRBPRKCBGSK3B | |
| SCHEMBL6634786 | 0.84 | PRKCB (0.44) | EDNRBPRKCBGSK3B | |
| SCHEMBL6636803 | 0.83 | PDE4A (0.52) | MEN1KMT2APDE4APDE4BPDE4C | |
| SCHEMBL7610547 | 0.83 | EDNRB (0.49) | PDE4APDE4BPDE4CPDE4DCNR1 | |
| SCHEMBL6640973 | 0.81 | ACAT1 (0.52) | PDE4APDE4BPDE4CPDE4DEDNRB | |
| SCHEMBL27390503 | 0.80 | CCNA2 (0.47) | EDNRBPRKCBGSK3BTNFLITAF | |
| SCHEMBL8325752 | 0.79 | PDE4A (0.49) | MEN1KMT2APDE4APDE4BPDE4C | |
| SCHEMBL6634085 | 0.79 | PDE4A (0.49) | MEN1KMT2APDE4APDE4BPDE4C | |
| SCHEMBL6634839 | 0.78 | ACAT1 (0.59) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1065243-C | Naphthyridine derivs. | SUMITOMO PHARMA (JP) | 2001-05-02 | — | — | CN | disclosed |
| CN-1191536-A | Naphthyridine derivs. | SUMITOMO PHARMA (JP) | 1998-08-26 | — | — | CN | disclosed |