Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22269009 | 0.84 | ALDH1A1 (0.32) | — | |
| SCHEMBL23992193 | 0.82 | TDP1 (0.40) | TDP1 | |
| SCHEMBL14435611 | 0.80 | ALDH1A1 (0.30) | TDP1ALOX15 | |
| SCHEMBL15599465 | 0.77 | — | — | |
| SCHEMBL26965734 | 0.77 | — | — | |
| SCHEMBL10503813 | 0.74 | — | — | |
| SCHEMBL17029292 | 0.74 | — | — | |
| SCHEMBL10503805 | 0.74 | — | — | |
| 2-Methyl-(E)-2-Butenal SCHEMBL28158266 | 0.73 | TDP1 (0.60) | TDP1LMNAALOX15BLMPMP22 | |
| SCHEMBL8717337 | 0.72 | TSHR (0.50) | TDP1LMNABLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024059878-A9 | DRUGS TARGETING TELOMERASE REVERSE TRANSCRIPTASE (TERT) FOR TREATMENT OF CANCERS | BROWN UNIVERSITY (US) | 2024-07-04 | — | — | WO | disclosed |