Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 15/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 15/20 | 0.48 |
| ▸ | F10 | P00742 | 6/20 | 0.48 |
| ▸ | F2 | P00734 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7420891 | 1.00 | ITGB3 (0.48) | ITGB3ITGA2BF10F2LMNA | |
| SCHEMBL7410866 | 1.00 | ITGB3 (0.48) | ITGB3ITGA2BF10F2LMNA | |
| SCHEMBL7421976 | 0.95 | ITGB3 (0.51) | ITGB3ITGA2BF10F2LMNA | |
| SCHEMBL7422392 | 0.91 | ITGB3 (0.46) | ITGB3ITGA2BF10F2LMNA | |
| SCHEMBL7533394 | 0.89 | ITGB3 (0.46) | ITGB3ITGA2BF10F2PRSS1 | |
| SCHEMBL7420050 | 0.89 | ITGB3 (0.46) | ITGB3ITGA2BF10F2PRSS1 | |
| SCHEMBL7533390 | 0.89 | ITGB3 (0.46) | ITGB3ITGA2BF10F2PRSS1 | |
| SCHEMBL7419407 | 0.89 | ITGB3 (0.52) | ITGB3ITGA2BF10F2 | |
| SCHEMBL7412389 | 0.89 | ITGB3 (0.52) | ITGB3ITGA2BF10F2 | |
| SCHEMBL7421592 | 0.88 | ITGB3 (0.46) | ITGB3ITGA2BF10F2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1054842-C | Platelet aggregation inhibitors | SEARLE & CO (US) | 2000-07-26 | — | — | CN | disclosed |
| CN-1124957-A | 1-amidinophenyl-pyrrolidones piperidinones azetinones as platelet aggregation inhibitors | SEARLE & CO (US) | 1996-06-19 | — | — | CN | disclosed |