Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 13/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 13/20 | 0.46 |
| ▸ | F10 | P00742 | 7/20 | 0.40 |
| ▸ | F2 | P00734 | 5/20 | 0.40 |
| ▸ | F9 | P00740 | 3/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 7/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 6/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 6/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7410866 | 0.89 | ITGB3 (0.48) | ITGB3ITGA2BF10F2PRSS1 | |
| SCHEMBL7420891 | 0.89 | ITGB3 (0.48) | ITGB3ITGA2BF10F2PRSS1 | |
| SCHEMBL27366188 | 0.89 | ITGB3 (0.48) | ITGB3ITGA2BF10F2PRSS1 | |
| SCHEMBL7423978 | 0.89 | ITGB3 (0.41) | ITGB3ITGA2BF9 | |
| SCHEMBL7420056 | 0.87 | LMNA (0.33) | ITGB3ITGA2B | |
| SCHEMBL7422392 | 0.87 | ITGB3 (0.46) | ITGB3ITGA2BF10F2F9 | |
| SCHEMBL7533390 | 0.86 | ITGB3 (0.46) | ITGB3ITGA2BF10F2F9 | |
| SCHEMBL7533394 | 0.86 | ITGB3 (0.46) | ITGB3ITGA2BF10F2F9 | |
| SCHEMBL7418867 | 0.84 | ITGB3 (0.51) | ITGB3ITGA2BF10F2F9 | |
| SCHEMBL7418871 | 0.84 | ITGB3 (0.51) | ITGB3ITGA2BF10F2F9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0691953-B1 | 1-AMIDINOPHENYL-PYRROLIDONES/ PIPERIDINONES AS PLATELET AGGREGATION INHIBITORS | SEARLE & CO (US) | 2000-08-02 | — | — | EP | disclosed |
| WO-1994022820-A1 | 1-AMIDINOPHENYL-PYRROLIDONES PIPERIDINONES AZETINONES AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1994-10-13 | — | — | WO | disclosed |