Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | CNR2 | P34972 | 14/20 | 0.36 |
| ▸ | CNR1 | P21554 | 10/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | MYC | P01106 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL217768 | 0.77 | CNR2 (0.60) | CNR2CNR1ALDH1A1 | |
| SCHEMBL13716013 | 0.76 | CNR2 (0.62) | CNR2CNR1 | |
| SCHEMBL5540993 | 0.73 | CNR2 (0.48) | CNR2CNR1BRD4CREBBP | |
| SCHEMBL2736618 | 0.71 | CNR2 (0.41) | CNR2CNR1MAPTBRD4CREBBP | |
| SCHEMBL26088619 | 0.71 | CNR2 (0.47) | CNR2CNR1ALDH1A1HPGD | |
| SCHEMBL2736907 | 0.70 | CNR2 (0.49) | MEN1KMT2ACNR2CNR1ALDH1A1 | |
| SCHEMBL26089078 | 0.70 | CNR2 (0.49) | MEN1KMT2ACNR2CNR1ALDH1A1 | |
| SCHEMBL13990928 | 0.69 | CNR2 (0.47) | KMT2ACNR2CNR1ALDH1A1HPGD | |
| SCHEMBL2736603 | 0.69 | BRPF1 (0.40) | CNR2CNR1 | |
| SCHEMBL14215376 | 0.69 | CNR2 (0.42) | CNR2CNR1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8088924-B2 | Pyridone derivatives having a binding activity to the cannabinoid type 2 receptor | SHIONOGI & CO., LTD. (JP) | 2012-01-03 | — | — | US | disclosed |
| US-20100081686-A1 | Pyridone derivatives having a binding activity to the cannabinoid type 2 recepter | TADA YUKIO | 2010-04-01 | — | — | US | disclosed |
| US-7652141-B2 | Immunosuppressants, analgesics, antiinflammatory agents | SHIONOGI & CO., LTD. (JP) | 2010-01-26 | — | — | US | disclosed |
| US-20080312292-A1 | Antipruritics | YASUI KIYOSHI | 2008-12-18 | — | — | US | disclosed |
| US-20070027144-A1 | Novel use of cannabinoid receptor agonist | SHIONOGI & CO., LTD. (JP) | 2007-02-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070027144-A1 | Novel use of cannabinoid receptor agonist | CNR2, CNR1, OPRM1 | MEN1 4737/4885KMT2A 2110/4885CNR2 1/4885 |
| US-20100081686-A1 | Pyridone derivatives having a binding activity to the cannabinoid type 2 recepter | CNR2, CNR1, NPY2R | MEN1 3159/4885KMT2A 2963/4885CNR2 1/4885 |
| US-20080312292-A1 | Antipruritics | CNR1, CNR2, OPRL1 | MEN1 4507/4885KMT2A 2819/4885CNR2 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.