Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.37 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.37 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CKS1B | P61024 | 1/20 | 0.36 |
| ▸ | SKP1 | P63208 | 1/20 | 0.36 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20756575 | 0.80 | BLM (0.57) | BLMALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL180620 | 0.80 | — | — | |
| SCHEMBL2739418 | 0.80 | BLM (0.57) | BLMALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL9530974 | 0.79 | BLM (0.50) | BLMALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL21765879 | 0.73 | L3MBTL1 (0.56) | BLMALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL802314 | 0.72 | CYP1A2 (0.54) | BLMALDH1A1KMT2ACHRNB2CHRNA3 | |
| SCHEMBL15742973 | 0.72 | BLM (0.55) | BLMALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL196593 | 0.72 | TDP1 (0.54) | BLMALDH1A1MEN1KMT2ATSHR | |
| Aziridine SCHEMBL27588415 | 0.72 | CHRNB2 (0.52) | BLMALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL12313804 | 0.71 | BLM (0.46) | BLMALDH1A1MEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1098716-A | Vasopressin antagonists and oxytocin antagonists | OTSUKA CHEMICAL CO LTD (JP) | 1995-02-15 | — | — | CN | disclosed |
| CN-1066653-A | BENZOHETEROCYCLIC COMPOUNDS | OTSUKA PHARMA CO LTD (JP) | 1992-12-02 | — | — | CN | disclosed |