Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 12/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LOX | P28300 | 2/20 | 0.39 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
| ▸ | GAB1 | Q13480 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8632622 | 0.98 | CA2 (0.49) | CA2SMN1; SMN2LOXAKT1GAB1 | |
| SCHEMBL4645445 | 0.86 | CA2 (0.44) | CA2LOX | |
| SCHEMBL10341122 | 0.81 | CA2 (0.61) | CA2LOX | |
| SCHEMBL18427649 | 0.81 | MEN1 (0.40) | CA2SMN1; SMN2LOX | |
| SCHEMBL23391726 | 0.80 | CA2 (0.47) | CA2LOX | |
| SCHEMBL10340958 | 0.80 | CA2 (0.59) | CA2LOX | |
| SCHEMBL10341129 | 0.80 | ALDH1A1 (0.49) | CA2LOX | |
| SCHEMBL10340984 | 0.79 | CA2 (0.60) | CA2LOX | |
| Hydrochloric Acid SCHEMBL10341115 | 0.79 | CA2 (0.46) | CA2LOX | |
| SCHEMBL10340977 | 0.78 | CA2 (0.41) | CA2LOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1064965-C | Novel sulfonamides compound and its use as medicine | HOFFMANN LA ROCHE (CH) | 2001-04-25 | — | — | CN | disclosed |
| CN-1132751-A | Novel sulfonamides compound and its use as medicine | HOFFMANN LA ROCHE (CH) | 1996-10-09 | — | — | CN | disclosed |