Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | SCN4A | P35499 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.45 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.45 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7422735 | 0.87 | SMN1; SMN2 (0.60) | SMN1; SMN2HSD17B10NPC1LMNANPSR1 | |
| SCHEMBL12057492 | 0.87 | SMN1; SMN2 (0.60) | SMN1; SMN2HSD17B10NPC1LMNANPSR1 | |
| SCHEMBL6284656 | 0.87 | SMN1; SMN2 (0.60) | SMN1; SMN2HSD17B10NPC1LMNANPSR1 | |
| SCHEMBL5403510 | 0.84 | SMN1; SMN2 (0.60) | SMN1; SMN2HSD17B10NPC1LMNANPSR1 | |
| SCHEMBL2848716 | 0.84 | SMN1; SMN2 (0.60) | SMN1; SMN2HSD17B10NPC1LMNANPSR1 | |
| SCHEMBL15307926 | 0.84 | SMN1; SMN2 (0.60) | SMN1; SMN2HSD17B10NPC1LMNANPSR1 | |
| SCHEMBL3591879 | 0.83 | SMN1; SMN2 (0.67) | SMN1; SMN2HSD17B10NPC1LMNANPSR1 | |
| SCHEMBL11032344 | 0.83 | SMN1; SMN2 (0.67) | SMN1; SMN2HSD17B10NPC1LMNANPSR1 | |
| SCHEMBL4473488 | 0.83 | SMN1; SMN2 (0.67) | SMN1; SMN2HSD17B10NPC1LMNANPSR1 | |
| SCHEMBL8237595 | 0.82 | SMN1; SMN2 (0.58) | SMN1; SMN2HSD17B10NPC1LMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1064683-A | New beta-amino-alpha-hydroxycarboxylic acids and uses thereof | SANKYO CO (JP) | 1992-09-23 | — | — | CN | disclosed |