Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 1/20 | 0.47 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.47 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.44 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.44 |
| ▸ | CCR3 | P51677 | 5/20 | 0.43 |
| ▸ | HTR2A | P28223 | 3/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27390332 | 1.00 | CARM1 (0.47) | CARM1PRMT6CHRNB4CHRNA3CCR3 | |
| SCHEMBL8542199 | 0.84 | CARM1 (0.46) | CARM1PRMT6CHRNB4CHRNA3CCR3 | |
| SCHEMBL8548529 | 0.84 | CARM1 (0.46) | CARM1PRMT6CHRNB4CHRNA3CCR3 | |
| SCHEMBL8544330 | 0.74 | CARM1 (0.46) | CARM1PRMT6CHRNB4CHRNA3CCR3 | |
| SCHEMBL8543112 | 0.74 | CARM1 (0.46) | CARM1PRMT6CHRNB4CHRNA3CCR3 | |
| SCHEMBL8547957 | 0.74 | CARM1 (0.45) | CARM1PRMT6CHRNB4CHRNA3CCR3 | |
| SCHEMBL8547751 | 0.74 | CARM1 (0.45) | CARM1PRMT6CHRNB4CHRNA3CCR3 | |
| SCHEMBL8547953 | 0.73 | GRIN2B (0.54) | CARM1PRMT6HTR2AGRIN2B | |
| SCHEMBL8547747 | 0.73 | GRIN2B (0.54) | CARM1PRMT6HTR2AGRIN2B | |
| SCHEMBL8549788 | 0.72 | GRIN2B (0.54) | CARM1PRMT6HTR2AGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1064358-C | Benzyl piperidine derivatives | MERCK PATENT GMBH (DE) | 2001-04-11 | — | — | CN | disclosed |
| CN-1128762-A | Benzyl piperidine derivatives | MERCK PATENT GMBH (DE) | 1996-08-14 | — | — | CN | disclosed |