Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 1/20 | 0.45 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | CCR3 | P51677 | 2/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 6/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 6/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 5/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 5/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8547957 | 1.00 | CARM1 (0.45) | CARM1PRMT6HTR2ACCR3BCHE | |
| SCHEMBL8548016 | 0.91 | CARM1 (0.42) | CARM1PRMT6HTR2ACCR3 | |
| SCHEMBL8542975 | 0.89 | MAOA (0.49) | MAOAMAOB | |
| SCHEMBL8547677 | 0.81 | CARM1 (0.47) | CARM1PRMT6HTR2ACCR3BCHE | |
| SCHEMBL8547747 | 0.81 | GRIN2B (0.54) | CARM1PRMT6HTR2AMAOAMAOB | |
| SCHEMBL8547953 | 0.81 | GRIN2B (0.54) | CARM1PRMT6HTR2AMAOAMAOB | |
| SCHEMBL8540534 | 0.79 | CARM1 (0.43) | CARM1PRMT6HTR2ACCR3BCHE | |
| SCHEMBL8546422 | 0.77 | CARM1 (0.40) | CARM1PRMT6BCHECHRNB4CHRNA3 | |
| SCHEMBL8547951 | 0.77 | CARM1 (0.40) | CARM1PRMT6BCHECHRNB4CHRNA3 | |
| SCHEMBL8547562 | 0.76 | ACHE (0.49) | CARM1PRMT6HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709384-B1 | Benzylpiperidine derivatives having high affinity for binding sites of aminoacid receptors | MERCK PATENT GMBH (DE) | 1998-12-23 | — | — | EP | disclosed |
| EP-0709384-A1 | Benzylpiperidine derivatives having high affinity for binding sites of aminoacid receptors | MERCK PATENT GmbH (DE) | 1996-05-01 | — | — | EP | disclosed |