SCHEMBL27366598

SCHEMBL27366598

c1ccc(N(c2ccccn2)c2cc3c4ccccc4c(N(c4ccccc4)c4ccccn4)cc3c3ccccc23)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.36
HDAC6 Q9UBN7 2/20 0.35
CYP2D6 P10635 1/20 0.34
CYP2C19 P33261 1/20 0.34
MAOA P21397 2/20 0.33
MAOB P27338 2/20 0.33
CHKA P35790 1/20 0.33
CHRM2 P08172 1/20 0.33
ADRA2A P08913 1/20 0.33
ADRA2B P18089 1/20 0.33
ADRA2C P18825 1/20 0.33
DRD1 P21728 1/20 0.33
SLC6A2 P23975 1/20 0.33
HTR2A P28223 1/20 0.33
SLC6A4 P31645 1/20 0.33
ADRA1A P35348 1/20 0.33
HRH1 P35367 1/20 0.33
OPRK1 P41145 1/20 0.33
SLC6A3 Q01959 1/20 0.33
KCNH2 Q12809 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13250591 0.88 ALDH1A1 (0.39) ALDH1A1HDAC6CYP2D6CYP2C19MAOA
SCHEMBL13321045 0.84 ALDH1A1 (0.35) ALDH1A1HDAC6CYP2D6CYP2C19MAOA
SCHEMBL13321039 0.83 ALDH1A1 (0.36) ALDH1A1HDAC6CYP2D6CYP2C19MAOA
SCHEMBL27366599 0.83 LMNA (0.35) ALDH1A1CYP2D6CYP2C19MAOAMAOB
SCHEMBL13320962 0.81 ALDH1A1 (0.33) ALDH1A1HDAC6CYP2D6CYP2C19MAOA
SCHEMBL17342431 0.81 ALDH1A1 (0.35) ALDH1A1HDAC6CYP2D6CYP2C19MAOA
SCHEMBL15250287 0.80
SCHEMBL31142139 0.80 ALDH1A1 (0.39) ALDH1A1CYP2D6CYP2C19TSHRKDM4E
SCHEMBL134697 0.80 ALDH1A1 (0.39) ALDH1A1CYP2D6CYP2C19TSHRKDM4E
SCHEMBL4647647 0.80 ALDH1A1 (0.45) ALDH1A1HDAC6CYP2D6CYP2C19MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024035190-A1 ORGANIC LIGHT-EMITTING DIODE AND ORGANIC COMPOUND 솔루스첨단소재 주식회사 2024-02-15 WO disclosed