Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | TOP2A | P11388 | 12/20 | 0.50 |
| ▸ | TOP2B | Q02880 | 7/20 | 0.50 |
| ▸ | TOP1 | P11387 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | XBP1 | P17861 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.45 |
| ▸ | FLT4 | P35916 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | RARB | P10826 | 1/20 | 0.45 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8890224 | 1.00 | KMT2A (0.57) | KMT2ATOP2ATOP2BTOP1KDM4E | |
| Hydrochloric Acid SCHEMBL8800189 | 0.99 | KMT2A (0.57) | KMT2ATOP2ATOP2BTOP1KDM4E | |
| SCHEMBL5868717 | 0.89 | KMT2A (0.60) | KMT2ATOP2ATOP2BTOP1ALDH1A1 | |
| SCHEMBL8619695 | 0.89 | KMT2A (0.60) | KMT2ATOP2ATOP2BTOP1ALDH1A1 | |
| SCHEMBL9088866 | 0.85 | KMT2A (0.60) | KMT2ATOP2ATOP2BTOP1ALDH1A1 | |
| SCHEMBL9869658 | 0.84 | KMT2A (0.69) | KMT2ATOP2ATOP2BTOP1ALDH1A1 | |
| SCHEMBL9085092 | 0.83 | KMT2A (0.57) | KMT2ATOP2ATOP2BTOP1ALDH1A1 | |
| SCHEMBL9088918 | 0.81 | KMT2A (0.55) | KMT2ATOP2ATOP2BTOP1EPHA2 | |
| SCHEMBL8888976 | 0.81 | POLB (0.58) | KMT2ATOP2ATOP2BALDH1A1POLB | |
| SCHEMBL8888963 | 0.81 | POLB (0.58) | KMT2ATOP2ATOP2BALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1064357-C | Novel antimicrobial 5-(N-heterosubstituted amino) quinolones | PROCTER & GAMBLE (US) | 2001-04-11 | — | — | CN | claimed |