Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | TOP2A | P11388 | 12/20 | 0.48 |
| ▸ | TOP2B | Q02880 | 7/20 | 0.48 |
| ▸ | TOP1 | P11387 | 4/20 | 0.48 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.43 |
| ▸ | FLT4 | P35916 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | RARB | P10826 | 1/20 | 0.43 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.43 |
| ▸ | MATK | P42679 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | MAPKAPK3 | Q16644 | 1/20 | 0.43 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.43 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9088866 | 0.92 | KMT2A (0.60) | KMT2ATOP2ATOP2BTOP1EPHA2 | |
| SCHEMBL8619695 | 0.92 | KMT2A (0.60) | KMT2ATOP2ATOP2BTOP1EPHA2 | |
| SCHEMBL9085092 | 0.89 | KMT2A (0.57) | KMT2ATOP2ATOP2BTOP1EPHA2 | |
| SCHEMBL9086611 | 0.87 | KCNH2 (0.50) | KMT2ATOP2ATOP2BTOP1EPHA2 | |
| SCHEMBL5868717 | 0.83 | KMT2A (0.60) | KMT2ATOP2ATOP2BTOP1EPHA2 | |
| SCHEMBL8625264 | 0.82 | KMT2A (0.60) | KMT2ATOP2ATOP2BTOP1EPHA2 | |
| SCHEMBL9087203 | 0.82 | KMT2A (0.37) | KMT2ATOP2ATOP2BTOP1EPHA2 | |
| SCHEMBL9869658 | 0.81 | KMT2A (0.69) | KMT2ATOP2ATOP2BTOP1 | |
| SCHEMBL9088336 | 0.81 | PIM3 (0.48) | TOP2ATOP2BTOP1GSK3BRPS6KB1 | |
| SCHEMBL9089412 | 0.81 | POLB (0.56) | KMT2ATOP2ATOP2BGSK3BRPS6KB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5585491-A | Antibacterial agents | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1996-12-17 | — | — | US | disclosed |
| EP-0398967-A1 | ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 1990-11-28 | — | — | EP | disclosed |
| US-4920120-A | 3-CARBOXY, 4-OXO, 6-FLUORO, 7-NITROGEN-CONTAINING RING 1,4-DIHYDRO-1,8-NAPHTHYRIDINES | WARNER-LAMBERT COMPANY (US) | 1990-04-24 | — | — | US | disclosed |
| EP-0326891-A2 | Antibacterial agents | WARNER-LAMBERT COMPANY (US) | 1989-08-09 | — | — | EP | disclosed |
| WO-1989006649-A2 | ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 1989-07-27 | — | — | WO | disclosed |