Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.69 |
| ▸ | TOP2A | P11388 | 15/20 | 0.64 |
| ▸ | TOP1 | P11387 | 3/20 | 0.64 |
| ▸ | TOP2B | Q02880 | 10/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.58 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.58 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.58 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10767292 | 0.91 | ALDH1A1 (0.69) | KMT2ATOP2ATOP1TOP2BALDH1A1 | |
| SCHEMBL9662129 | 0.90 | KMT2A (0.66) | KMT2ATOP2ATOP1TOP2BALDH1A1 | |
| SCHEMBL9662150 | 0.90 | KMT2A (0.66) | KMT2ATOP2ATOP1TOP2BALDH1A1 | |
| SCHEMBL29080644 | 0.90 | KDM4E (0.58) | KMT2ATOP2ATOP1TOP2BALDH1A1 | |
| SCHEMBL30626277 | 0.90 | KDM4E (0.58) | KMT2ATOP2ATOP1TOP2BALDH1A1 | |
| SCHEMBL10373907 | 0.90 | TOP2A (0.72) | KMT2ATOP2ATOP1TOP2BALDH1A1 | |
| SCHEMBL9662360 | 0.90 | KMT2A (0.63) | KMT2ATOP2ATOP1TOP2BALDH1A1 | |
| SCHEMBL10442795 | 0.89 | KMT2A (0.56) | KMT2ATOP2ATOP1TOP2BALDH1A1 | |
| Hydrochloric Acid SCHEMBL9773874 | 0.89 | TOP1 (0.66) | KMT2ATOP2ATOP1TOP2B | |
| SCHEMBL9869412 | 0.89 | TOP2A (0.61) | KMT2ATOP2ATOP1TOP2BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4981854-A | BACTERICIDES, ANIMAL GROWTH REGUALTORS | BAYER AKTIENGESELLSCHAFT (DE) | 1991-01-01 | — | — | US | disclosed |
| US-4980353-A | BACTERICIDES, ANIMAL GROWTH REGULATORS | BAYER AKTIENGESELLSCHAFT (DE) | 1990-12-25 | — | — | US | disclosed |