Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CTSV | O60911 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MYC | P01106 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.43 |
| ▸ | ANO2 | Q9NQ90 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CDC25B | P30305 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8683506 | 0.90 | PKM (0.56) | PKMTDP1KDM4EPOLBCTDSP1 | |
| SCHEMBL7350584 | 0.85 | TDP1 (0.46) | PKMTDP1KDM4EPOLBCTDSP1 | |
| SCHEMBL8703261 | 0.84 | CFD (0.49) | PKMTDP1KDM4EPOLBCTDSP1 | |
| SCHEMBL1554733 | 0.83 | KDM4E (0.61) | PKMTDP1KDM4EPOLBCTDSP1 | |
| SCHEMBL7847617 | 0.83 | PKM (0.65) | PKMTDP1KDM4EPOLBCTDSP1 | |
| SCHEMBL1447280 | 0.83 | PKM (0.56) | PKMTDP1KDM4EPOLBCTDSP1 | |
| SCHEMBL30105934 | 0.83 | PKM (0.69) | PKMTDP1KDM4EPOLBCTDSP1 | |
| SCHEMBL621983 | 0.83 | PKM (0.69) | PKMTDP1KDM4EPOLBCTDSP1 | |
| SCHEMBL3478112 | 0.82 | TSHR (0.59) | PKMTDP1POLBL3MBTL1TSHR | |
| SCHEMBL8671212 | 0.82 | TSHR (0.59) | PKMTDP1POLBL3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1053063-A | Quinazoline derivant and preparation method thereof | FUJISAWA PHARMACEUTICAL CO (JP) | 1991-07-17 | — | — | CN | disclosed |