Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HNF4A | P41235 | 1/20 | 0.54 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.54 |
| ▸ | RORC | P51449 | 1/20 | 0.51 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.46 |
| ▸ | METTL14 | Q9HCE5 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2736831 | 0.83 | RORC (0.47) | RORC | |
| SCHEMBL12309659 | 0.83 | — | — | |
| SCHEMBL2737049 | 0.80 | — | — | |
| SCHEMBL2737047 | 0.80 | — | — | |
| SCHEMBL2736543 | 0.79 | — | — | |
| SCHEMBL2736709 | 0.78 | ALDH1A1 (0.46) | — | |
| SCHEMBL2736688 | 0.77 | — | — | |
| SCHEMBL12309660 | 0.76 | — | — | |
| SCHEMBL10207670 | 0.76 | RORC (0.49) | RORC | |
| SCHEMBL2737152 | 0.75 | RORC (0.52) | RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2402314-A1 | (Aza)indole derivative and use thereof for medical purposes | Kissei Pharmaceutical Co., Ltd. (JP) | 2012-01-04 | — | — | EP | disclosed |