Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | CTRC | Q99895 | 1/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8652824 | 0.87 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL27369487 | 0.82 | POLB (0.36) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL27367778 | 0.82 | POLB (0.36) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL27346346 | 0.80 | TDP1 (0.35) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL27374490 | 0.78 | ALDH1A1 (0.33) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL27370288 | 0.76 | NPC1 (0.35) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL27401108 | 0.75 | ALDH1A1 (0.32) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL27317935 | 0.75 | ALDH1A1 (0.33) | ALDH1A1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL27527209 | 0.75 | MAPT (0.32) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL27346343 | 0.75 | GAA (0.32) | ALDH1A1MEN1KMT2AKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1053065-A | AZAOXINDOLE DERIVATIVES | PFIZER (US) | 1991-07-17 | — | — | CN | disclosed |