Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.34 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27369487 | 0.92 | POLB (0.36) | POLBALDH1A1SMN1; SMN2LMNAHTT | |
| SCHEMBL8655676 | 0.87 | POLB (0.41) | POLBALDH1A1SMN1; SMN2LMNAHTT | |
| SCHEMBL27530089 | 0.84 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL27366764 | 0.82 | ALDH1A1 (0.36) | POLBALDH1A1SMN1; SMN2HTTKMT2A | |
| SCHEMBL27346346 | 0.82 | TDP1 (0.35) | POLBALDH1A1SMN1; SMN2KMT2AMAPT | |
| SCHEMBL27374490 | 0.81 | ALDH1A1 (0.33) | POLBALDH1A1SMN1; SMN2KMT2AMAPT | |
| SCHEMBL8654232 | 0.79 | POLB (0.41) | POLBALDH1A1SMN1; SMN2LMNAHTT | |
| SCHEMBL27370288 | 0.78 | NPC1 (0.35) | POLBALDH1A1SMN1; SMN2KMT2AMAPT | |
| SCHEMBL27401108 | 0.78 | ALDH1A1 (0.32) | ALDH1A1SMN1; SMN2LMNAHTTKMT2A | |
| SCHEMBL27527209 | 0.78 | MAPT (0.32) | POLBALDH1A1SMN1; SMN2LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1053065-A | AZAOXINDOLE DERIVATIVES | PFIZER (US) | 1991-07-17 | — | — | CN | disclosed |