SCHEMBL27367265

SCHEMBL27367265

CSc1c(Cl)cccc1C(=O)Cl

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.47
TSHR P16473 1/20 0.42
CES2 O00748 1/20 0.42
CES1 P23141 1/20 0.42
ALOX15 P16050 1/20 0.39
POLB P06746 2/20 0.38
MAPT P10636 4/20 0.38
KMT2A Q03164 4/20 0.38
MEN1 O00255 3/20 0.38
SMN1; SMN2 Q16637 1/20 0.37
LMNA P02545 2/20 0.36
KDM4E B2RXH2 1/20 0.36
RAB9A P51151 1/20 0.36
TAS1R3 Q7RTX0 1/20 0.36
TAS1R1 Q7RTX1 1/20 0.36
TAS1R2 Q8TE23 1/20 0.36
USP2 O75604 1/20 0.36
MT-CO2 P00403 1/20 0.36
TTR P02766 1/20 0.36
PLA2G1B P04054 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8493569 0.85 TSHR (0.57) ALDH1A1TSHRCES2CES1ALOX15
SCHEMBL8390748 0.82 ALDH1A1 (0.34) ALDH1A1TSHRCES2CES1ALOX15
SCHEMBL27388138 0.81 ALDH1A1 (0.41) ALDH1A1ALOX15POLBKMT2AMEN1
SCHEMBL27447185 0.80 ALDH1A1 (0.42) ALDH1A1TSHRCES2CES1ALOX15
SCHEMBL31620807 0.80 NR4A2 (0.49) ALDH1A1TSHRPOLBMAPTKMT2A
SCHEMBL27447776 0.79 ALDH1A1 (0.57) ALDH1A1TSHRCES2CES1ALOX15
SCHEMBL28874729 0.77 ALDH1A1 (0.46) ALDH1A1TSHRCES2CES1ALOX15
SCHEMBL5594805 0.76 CYP1A2 (0.43) ALDH1A1TSHRMAPTKMT2AMEN1
SCHEMBL8307823 0.74 ALDH1A1 (0.37) ALDH1A1TSHRCES2CES1ALOX15
SCHEMBL108670 0.74 ALDH1A1 (0.52) ALDH1A1TSHRCES2CES1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1070400-A Benzoglyoxaline FISONS PLC (GB) 1993-03-31 CN disclosed