Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8391857 | 0.86 | ALDH1A1 (0.40) | ALDH1A1HPGDUSP2SORT1KMT2A | |
| SCHEMBL8390748 | 0.83 | ALDH1A1 (0.34) | ALDH1A1ALOX15HPGDHSD17B10KMT2A | |
| SCHEMBL8391653 | 0.81 | ABL1 (0.41) | ALDH1A1HPGDKMT2ATSHRHTT | |
| SCHEMBL29544731 | 0.77 | HPGD (0.55) | ALDH1A1ALOX15HPGDUSP2SORT1 | |
| SCHEMBL9860903 | 0.77 | HPGD (0.55) | ALDH1A1ALOX15HPGDUSP2SORT1 | |
| SCHEMBL9712390 | 0.76 | HPGD (0.42) | ALDH1A1ALOX15HPGDUSP2SORT1 | |
| SCHEMBL8389398 | 0.75 | SORT1 (0.42) | ALDH1A1HPGDUSP2SORT1KMT2A | |
| SCHEMBL7938468 | 0.75 | ALDH1A1 (0.43) | ALDH1A1ALOX15HPGDUSP2SORT1 | |
| SCHEMBL8309958 | 0.75 | HSD17B10 (0.39) | ALDH1A1HPGDSORT1HSD17B10KMT2A | |
| SCHEMBL27367265 | 0.74 | ALDH1A1 (0.47) | ALDH1A1ALOX15HPGDUSP2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0918056-A1 | Herbicides | RHONE-POULENC AGRICULTURE LTD. (GB) | 1999-05-26 | — | — | EP | disclosed |
| EP-0625508-B1 | Sulfur-containing derivatives of 2-cyano-1,3-diones and their use as herbicides | RHONE POULENC AGRICULTURE (GB) | 1998-08-19 | — | — | EP | disclosed |
| EP-0625508-A2 | Sulfur-containing derivatives of 2-cyano-1,3-diones and their use as herbicides | RHONE POULENC AGRICULTURE LTD. (GB) | 1994-11-23 | — | — | EP | disclosed |