Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 17/20 | 0.55 |
| ▸ | MERTK | Q12866 | 17/20 | 0.55 |
| ▸ | TYRO3 | Q06418 | 4/20 | 0.55 |
| ▸ | MET | P08581 | 1/20 | 0.40 |
| ▸ | BCL2 | P10415 | 2/20 | 0.35 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27367326 | 0.83 | AXL (0.78) | AXLMERTKTYRO3 | |
| SCHEMBL27367116 | 0.76 | MERTK (0.60) | AXLMERTKTYRO3 | |
| SCHEMBL27367327 | 0.73 | MERTK (0.63) | AXLMERTKTYRO3 | |
| SCHEMBL27367325 | 0.72 | MERTK (0.77) | AXLMERTKTYRO3 | |
| SCHEMBL27367037 | 0.71 | MERTK (0.83) | AXLMERTKTYRO3 | |
| SCHEMBL32685181 | 0.71 | MERTK (1.00) | AXLMERTKTYRO3 | |
| SCHEMBL27365942 | 0.71 | MERTK (1.00) | AXLMERTKTYRO3 | |
| SCHEMBL27366825 | 0.71 | MERTK (0.73) | AXLMERTKTYRO3 | |
| SCHEMBL27367248 | 0.71 | MERTK (0.70) | AXLMERTKTYRO3 | |
| SCHEMBL27366841 | 0.69 | MERTK (0.75) | AXLMERTKTYRO3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024039842-A2 | INHIBITORS OF TAM RECEPTORS | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2024-02-22 | — | — | WO | disclosed |