Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27440189 | 0.80 | S100A9 (0.33) | KMT2ANPC1TLR9MAPTHTT | |
| SCHEMBL27267594 | 0.73 | KMT2A (0.43) | KMT2AMAPTHTTALDH1A1NPSR1 | |
| Hydrochloric Acid SCHEMBL27547413 | 0.73 | HPGD (0.40) | KMT2AHTTALDH1A1L3MBTL1HPGD | |
| SCHEMBL2490205 | 0.69 | — | — | |
| SCHEMBL27892010 | 0.69 | — | — | |
| SCHEMBL13663843 | 0.68 | KMT2A (0.36) | KMT2AMAPTHTTALDH1A1L3MBTL1 | |
| SCHEMBL1187131 | 0.68 | — | — | |
| SCHEMBL850260 | 0.68 | — | — | |
| SCHEMBL2373825 | 0.67 | MEN1 (0.61) | KMT2ANPC1TLR9MAPTHTT | |
| SCHEMBL28901040 | 0.67 | KMT2A (0.35) | KMT2AMAPTHTTALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101316587-B | Substituted pyrazole compounds | MIIKANA THERAPEUTICS INC | 2013-04-03 | — | — | CN | disclosed |
| CN-101316587-A | Substituted pyrazole compounds | MIIKANA THERAPEUTICS INC (US) | 2008-12-03 | — | — | CN | disclosed |
| CN-1054590-A | The benzoic acid herbicides that 6-aryl-2-replaces | FMC CORP (US) | 1991-09-18 | — | — | CN | disclosed |