SCHEMBL28901040

SCHEMBL28901040

Cc1ncc(S(=O)(=O)O)c(C)n1.[NaH]

nearest known ligand 0.35

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.35
NTRK1 P04629 1/20 0.33
MYC P01106 1/20 0.31
KDM4E B2RXH2 1/20 0.30
ALDH1A1 P00352 1/20 0.30
LMNA P02545 1/20 0.30
MAPT P10636 1/20 0.30
HTT P42858 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13663843 0.98 KMT2A (0.36) KMT2ANTRK1MYCKDM4EALDH1A1
SCHEMBL27267594 0.78 KMT2A (0.43) KMT2ANTRK1MYCALDH1A1LMNA
SCHEMBL27620670 0.78 TET2 (0.34) KMT2ANTRK1MYCKDM4EALDH1A1
SCHEMBL3018205 0.78 KMT2A (0.39) KMT2ANTRK1
SCHEMBL27590171 0.72 PTGS2 (0.33) KMT2ANTRK1ALDH1A1LMNAMAPT
SCHEMBL27679901 0.72 KMT2A (0.31) KMT2A
SCHEMBL14837791 0.69 NTRK1 (0.37) NTRK1
SCHEMBL27272062 0.69 ALDH1A1 (0.50) KMT2ANTRK1KDM4EALDH1A1LMNA
SCHEMBL27590169 0.69 MAPT (0.33) LMNAMAPTHTTSMN1; SMN2
SCHEMBL27267602 0.69 ALDH1A1 (0.50) KMT2AALDH1A1SMN1; SMN2L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111848834-B Application of cationic polymer modified by fluorine-containing compound in preparing medicine for transmucosal administration 苏州大学 2023-01-24 CN disclosed
CN-111848834-A Application of cationic polymer modified by fluorine-containing compound in preparing transmucosal drug delivery of drug 苏州大学 2020-10-30 CN disclosed
CN-111848832-A Application of fluorine-containing compound modified cationic polymer as drug carrier and preparation method thereof 苏州大学 2020-10-30 CN disclosed