Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.39 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24920047 | 0.85 | MAPT (0.46) | MAPTOPRM1ACE2GPR84SPHK1 | |
| SCHEMBL20411871 | 0.85 | MAPT (0.46) | MAPTOPRM1ACE2GPR84SPHK1 | |
| SCHEMBL10513603 | 0.82 | OPRM1 (0.48) | MAPTOPRM1ACE2GPR84CA1 | |
| SCHEMBL21467732 | 0.78 | DNM1 (0.46) | MAPTOPRM1ACE2GPR84SPHK1 | |
| SCHEMBL28779372 | 0.78 | MAPT (0.45) | MAPTOPRM1ACE2GPR84SPHK1 | |
| SCHEMBL20076558 | 0.78 | MAPT (0.45) | MAPTOPRM1ACE2GPR84SPHK1 | |
| SCHEMBL30110410 | 0.77 | OPRM1 (0.48) | MAPTOPRM1ACE2GPR84CA1 | |
| SCHEMBL6083417 | 0.76 | SPHK1 (0.50) | MAPTOPRM1ACE2GPR84SPHK1 | |
| SCHEMBL9754003 | 0.76 | SPHK1 (0.50) | MAPTOPRM1ACE2GPR84SPHK1 | |
| SCHEMBL22756700 | 0.75 | OPRM1 (0.46) | MAPTOPRM1ACE2CA1SPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024054807-A1 | COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS AND TDP-43 MODULATORS | BIOHAVEN THERAPEUTICS LTD. (VG) | 2024-03-14 | — | — | WO | disclosed |