Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
| ▸ | PNP | P00491 | 1/20 | 0.39 |
| ▸ | TYMS | P04818 | 2/20 | 0.39 |
| ▸ | HAO1 | Q9UJM8 | 3/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 2/20 | 0.36 |
| ▸ | PLK4 | O00444 | 1/20 | 0.34 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | METAP2 | P50579 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27534138 | 0.84 | HAO1 (0.37) | HAO1 | |
| SCHEMBL14860249 | 0.79 | NOTUM (0.48) | GRM5HAO1IDO1MAPTNOTUM | |
| SCHEMBL27451779 | 0.79 | NOTUM (0.48) | GRM5TYMSHAO1EGFRMAPT | |
| SCHEMBL27394027 | 0.79 | HAO1 (0.59) | TYMSHAO1LRRK2PLK4IDO1 | |
| SCHEMBL27392247 | 0.78 | HAO1 (0.55) | TYMSHAO1MAOAALDH1A1MAPK1 | |
| SCHEMBL3480583 | 0.77 | HPGD (0.41) | HAO1MAOAMAPTNOTUMALDH1A1 | |
| SCHEMBL27369979 | 0.77 | NOTUM (0.52) | HAO1LRRK2EGFRIDO1MAPT | |
| SCHEMBL27366450 | 0.76 | HDAC4 (0.38) | HAO1MAPTNOTUMALDH1A1 | |
| SCHEMBL3289392 | 0.74 | MAOA (0.48) | GRM5PNPTYMSMAOADDB1 | |
| SCHEMBL29543964 | 0.74 | MAOA (0.48) | GRM5PNPTYMSMAOADDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1063282-A | Pyrazole derivatives and preparation and application with weeding activity | SANKYO CO (JP) | 1992-08-05 | — | — | CN | disclosed |