Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.52 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | DHFR | P00374 | 3/20 | 0.45 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.45 |
| ▸ | PTGIR | P43119 | 1/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | EDNRA | P25101 | 1/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.40 |
| ▸ | TUBB | P07437 | 1/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.40 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.40 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.40 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14860249 | 0.80 | NOTUM (0.48) | NOTUMIDO1HTR1AHTR3AMAPT | |
| SCHEMBL3164341 | 0.78 | ACHE (0.54) | NOTUMIDO1DHFRPTGIRABCG2 | |
| SCHEMBL31425668 | 0.78 | ACHE (0.54) | NOTUMIDO1DHFRPTGIRABCG2 | |
| SCHEMBL27367462 | 0.77 | GRM5 (0.43) | NOTUMIDO1LRRK2MAPTEGFR | |
| SCHEMBL27451779 | 0.77 | NOTUM (0.48) | NOTUMDHFRCYP1A2CYP3A4MAPT | |
| SCHEMBL27394027 | 0.77 | HAO1 (0.59) | NOTUMIDO1LRRK2HAO1 | |
| SCHEMBL24433577 | 0.77 | ACHE (0.52) | NOTUMIDO1DHFRPTGIRABCG2 | |
| SCHEMBL27366450 | 0.76 | HDAC4 (0.38) | NOTUMCYP3A4MAPTHAO1 | |
| SCHEMBL10709610 | 0.75 | MTNR1A (0.57) | IDO1DHFRPTGIRABCG2HTR1A | |
| SCHEMBL3480583 | 0.75 | HPGD (0.41) | NOTUMMAPTTUBB4ATUBBTUBA3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1063282-A | Pyrazole derivatives and preparation and application with weeding activity | SANKYO CO (JP) | 1992-08-05 | — | — | CN | disclosed |